SCHEMBL6842214

SCHEMBL6842214

O=C1CC=CC=C1c1nc2ccccc2[nH]c1=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.54
RAB9A P51151 5/20 0.54
NPC1 O15118 4/20 0.54
HSD17B10 Q99714 4/20 0.48
CASP1 P29466 2/20 0.48
CASP7 P55210 2/20 0.48
LMNA P02545 1/20 0.48
GLA P06280 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.47
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
PLAUR Q03405 1/20 0.45
ADORA3 P0DMS8 1/20 0.45
ADORA1 P30542 1/20 0.45
HTT P42858 2/20 0.43
MAPT P10636 1/20 0.43
HTR3A P46098 1/20 0.43
HRH4 Q9H3N8 1/20 0.43
ALDH1A1 P00352 4/20 0.42
KHK P50053 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29820118 0.71 RAB9A (1.00) KDM4ERAB9ANPC1HSD17B10CASP1
SCHEMBL1902269 0.71 RAB9A (0.69) KDM4ERAB9ANPC1HSD17B10CASP1
SCHEMBL1901480 0.71 RAB9A (1.00) KDM4ERAB9ANPC1HSD17B10CASP1
SCHEMBL31448344 0.69 KDM4E (1.00) KDM4ERAB9ANPC1HSD17B10CASP1
SCHEMBL28362353 0.69 KDM4E (1.00) KDM4ERAB9ANPC1HSD17B10CASP1
SCHEMBL7804226 0.69 NPC1 (0.44) KDM4ERAB9ANPC1HSD17B10CASP1
Alloxazine SCHEMBL57289 0.68 RAB9A (0.60) KDM4ERAB9ANPC1HSD17B10CASP1
SCHEMBL4590581 0.68 NPC1 (0.42) KDM4ERAB9ANPC1HSD17B10LMNA
SCHEMBL30637069 0.68 KDM4E (0.75) KDM4ERAB9ANPC1HSD17B10CASP1
SCHEMBL29101809 0.68 KDM4E (0.75) KDM4ERAB9ANPC1HSD17B10CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6761874-B2 CATALYTIC HYDROGENATION OF 2-QUINOXALINONE COMPOUND COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2004-07-13 US disclosed
US-20030165421-A1 Process for the preparation of hydrogen peroxide COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2003-09-04 US disclosed