Alloxazine

Alloxazine

SCHEMBL57289

O=c1nc2[nH]c3ccccc3nc-2c(=O)[nH]1

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 7/20 0.60
NPC1 O15118 7/20 0.60
KDM4E B2RXH2 5/20 0.60
HSD17B10 Q99714 3/20 0.55
ALDH1A1 P00352 2/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
NPSR1 Q6W5P4 2/20 0.55
ABCB11 O95342 1/20 0.55
TP53 P04637 1/20 0.55
PKM P14618 1/20 0.55
CASP1 P29466 2/20 0.53
CASP7 P55210 2/20 0.53
LMNA P02545 1/20 0.53
GLA P06280 1/20 0.53
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
FGFR1 P11362 4/20 0.50
PDGFRB P09619 3/20 0.50
KDR P35968 3/20 0.50
GBA1 P04062 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1902269 0.89 RAB9A (0.69) RAB9ANPC1KDM4EHSD17B10ALDH1A1
SCHEMBL3473707 0.82 KMT2A (0.53) RAB9ANPC1KDM4EHSD17B10ALDH1A1
SCHEMBL3472182 0.80 RAB9A (0.36) RAB9ANPC1KDM4EHSD17B10CASP1
SCHEMBL24238258 0.78 HPGD (0.51) RAB9ANPC1KDM4EHSD17B10ALDH1A1
SCHEMBL21995498 0.78 MEN1 (0.55) RAB9ANPC1KDM4EHSD17B10ALDH1A1
SCHEMBL1901480 0.75 RAB9A (1.00) RAB9ANPC1KDM4EHSD17B10ALDH1A1
SCHEMBL29820118 0.75 RAB9A (1.00) RAB9ANPC1KDM4EHSD17B10ALDH1A1
SCHEMBL1782708 0.74 PARP1 (0.43) RAB9ANPC1KDM4EALDH1A1SMN1; SMN2
SCHEMBL24238263 0.74 KDM4E (0.43) RAB9ANPC1KDM4EALDH1A1SMN1; SMN2
SCHEMBL1976588 0.74 RAB9A (0.47) RAB9ANPC1KDM4EHSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1731 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260034277-A1 SYSTEMS AND METHODS FOR PATHOGEN INACTIVATION OF BLOOD PRODUCTS CERUS CORP (US) 2026-02-05 US claimed
US-12364949-B2 Method for electrochemical gas separation VERDOX, INC. (US) 2025-07-22 US claimed
US-12365850-B2 Water-miscible functional fluid, undiluted stock of water-miscible functional fluid, sterilizer for water-miscible functional fluid, and method of sterilizing water-miscible function fluid YUSHIRO CHEMICAL INDUSTRY CO., LTD. (JP) 2025-07-22 US claimed
EP-3934594-B1 ENERGY AUGMENTATION STRUCTURES FOR USE IN NON-INVASIVE IN-SITU PHOTOBIOMODULATION IMMUNOLIGHT LLC (US) 2025-05-28 EP claimed
US-20250144562-A1 ELECTROCHEMICAL CO2 CAPTURE WITH AIR STABLE REDOX SPECIES PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2025-05-08 US claimed
EP-4255626-B1 HETEROGENEOUS REDOX CATALYTIC SYSTEM ASOCIACION CENTRO DE INVESTIG COOPERATIVA EN BIOMATERIALES CIC BIOMAGUNE (ES) 2025-02-12 EP claimed
WO-2025019426-A1 ELECTROCHEMICAL CO2 CAPTURE WITH AIR STABLE REDOX SPECIES PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2025-01-23 WO claimed
EP-3367890-B1 A PHOTOACTIVATABLE DRUG FOR USE IN RADIOTHERAPY IMMUNOLIGHT LLC (US) 2024-12-04 EP claimed
CN-118994174-A Isoalloxazine compound, preparation method and application thereof in preparation of flexible non-binder zinc ion battery anode material 厦门大学 2024-11-22 CN claimed
US-12121746-B2 Energy augmentation structures, energy emitters or energy collectors containing the same, and their use in methods and systems for treating cell proliferation disorders IMMUNOLIGHT, LLC (US) 2024-10-22 US claimed
EP-0390132-A2 Electronic device MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 1990-10-03 EP claimed
EP-0384366-A2 Photosensitive recording element BASF Aktiengesellschaft (DE) 1990-08-29 EP claimed
US-4654378-A Process for the manufacture of high solids, free-flowing, granular poly(dimethyldiallyl ammonium chloride) CALGON CORPORATION (US) 1987-03-31 US claimed
US-4629696-A USING NADPH, A DIAPHORASE AND A REDOX PARTNER TO PRODUCE SUPEROXIDE, HYDROGEN PEROXIDE OR HYDROXYL RADICALS; QUANTITATIVE ANALYSIS BOEHRINGER MANNHEIM GMBH (DE) 1986-12-16 US claimed
EP-0105443-B1 METHOD OF SELECTIVELY PRODUCING REDUCED OXYGEN SPECIES AND REAGENTS SUITABLE THEREFOR Roche Diagnostics GmbH (DE) 1986-07-02 EP claimed
EP-0105443-A2 Method of selectively producing reduced oxygen species and reagents suitable therefor Roche Diagnostics GmbH (DE) 1984-04-18 EP claimed
EP-0030550-A1 ANTIHYPERTENSIVE AGENTS AND THEIR USE IN TREATMENT OF HYPERTENSION TRACHEWSKY, Daniel (US) 1981-06-24 EP claimed
US-4264601-A SUBSTITUTED ISOALLOXAZINES THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) 1981-04-28 US claimed
WO-1980002799-A1 ANTIHYPERTENSIVE AGENTS AND THEIR USE IN TREATMENT OF HYPERTENSION TRACHEWSKY D 1980-12-24 WO claimed
US-4111692-A ALIPHATIC NITROGEN COMPOUND, HALOGEN COMPOUND AS FREE RADICAL GENERATOR TOYO BOSEKI KABUSHIKI KAISHA (JP) 1978-09-05 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260034277-A1 SYSTEMS AND METHODS FOR PATHOGEN INACTIVATION OF BLOOD PRODUCTS PRF1, CFD, F5 RAB9A 3475/4885NPC1 1276/4885KDM4E 4393/4885
US-12121746-B2 Energy augmentation structures, energy emitters or energy collectors containing the same, and their use in methods and systems for treating cell proliferation disorders TK2, GFM1, HDGF RAB9A 4376/4885NPC1 1080/4885KDM4E 4628/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.