Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 1/20 | 0.50 |
| ▸ | FEN1 | P39748 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6843254 | 1.00 | ERCC5 (0.50) | ERCC5FEN1PTPN1CES2CES1 | |
| SCHEMBL3081491 | 0.78 | XDH (0.47) | PTPN1CES2CES1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3081493 | 0.78 | XDH (0.47) | PTPN1CES2CES1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6510709 | 0.77 | ERCC5 (0.72) | ERCC5FEN1PTPN1CES2CES1 | |
| SCHEMBL2776826 | 0.76 | CES2 (0.43) | ERCC5FEN1PTPN1CES2CES1 | |
| SCHEMBL3070004 | 0.76 | CES2 (0.43) | ERCC5FEN1PTPN1CES2CES1 | |
| SCHEMBL2776829 | 0.76 | CES2 (0.43) | ERCC5FEN1PTPN1CES2CES1 | |
| SCHEMBL6843271 | 0.74 | ERCC5 (0.53) | ERCC5FEN1PTPN1CES2CES1 | |
| SCHEMBL3382041 | 0.73 | HDAC8 (0.56) | ALDH1A1SMN1; SMN2PKMMAPTPOLB | |
| SCHEMBL3382039 | 0.73 | HDAC8 (0.56) | ALDH1A1SMN1; SMN2PKMMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861843-B1 | Fluorescent ionophoric compounds with a cryptand/crown-ether portion and a coumarin portion, their preparation and their use for measuring metal cation concentrations | TERUMO CARDIOVASCULAR SYS (US) | 2004-07-14 | — | — | EP | disclosed |
| US-5958782-A | FLUORESCENT IONOPHORIC COMPOUND IS DISCLOSED THAT INCLUDES A COMPLEXING MOIETY, SUCH AS A CRYPTAND OR CROWN-ETHER PORTION, AND A FLUORESCING MOIETY SUCH AS A COUMARIN PORTION | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-09-28 | — | — | US | disclosed |
| EP-0861843-A2 | Fluorescent ionophoric compounds with a cryptand/crown-ether portion and a coumarin portion, their preparation and their use for measuring metal cation concentrations | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-09-02 | — | — | EP | disclosed |