Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2B | P18089 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6646888 | 0.90 | ADRA2B (0.66) | ADRA2BSMN1; SMN2ALDH1A1CYP3A4TDP1 | |
| SCHEMBL6644025 | 0.89 | ADRA2B (0.69) | ADRA2BSMN1; SMN2ALDH1A1CYP3A4TDP1 | |
| SCHEMBL6838344 | 0.87 | ALDH1A1 (0.75) | ADRA2BSMN1; SMN2ALDH1A1CYP3A4TDP1 | |
| SCHEMBL6643434 | 0.87 | ADRA2B (0.70) | ADRA2BSMN1; SMN2ALDH1A1CYP3A4TDP1 | |
| SCHEMBL6843458 | 0.86 | ADRA2B (0.65) | ADRA2BSMN1; SMN2ALDH1A1CYP3A4TDP1 | |
| SCHEMBL6646799 | 0.85 | ALDH1A1 (0.67) | ADRA2BSMN1; SMN2ALDH1A1CYP3A4TDP1 | |
| SCHEMBL6645605 | 0.85 | GAA (0.75) | ADRA2BSMN1; SMN2ALDH1A1CYP3A4TDP1 | |
| SCHEMBL6644703 | 0.83 | ADRA2B (0.64) | ADRA2BSMN1; SMN2ALDH1A1CYP3A4TDP1 | |
| SCHEMBL6669539 | 0.82 | KMT2A (0.60) | ADRA2BSMN1; SMN2ALDH1A1CYP3A4TDP1 | |
| SCHEMBL7081755 | 0.82 | ADRA2B (0.60) | ADRA2BSMN1; SMN2ALDH1A1CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6767909-B2 | CARDIOVASCULAR DISORDERS; VASOCONSTRICTION | OY JUVANTIA PHARMA LTD. (FI) | 2004-07-27 | — | — | US | disclosed |