Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2319886 | 1.00 | USP2 (0.45) | USP2SMN1; SMN2NR1H2MAPK1HPGD | |
| SCHEMBL6843469 | 1.00 | USP2 (0.45) | USP2SMN1; SMN2NR1H2MAPK1HPGD | |
| Pyridine SCHEMBL28139409 | 0.88 | MAPK1 (0.43) | MAPK1GPR119 | |
| SCHEMBL16018 | 0.85 | NR1H2 (0.47) | USP2SMN1; SMN2NR1H2MAPK1HPGD | |
| SCHEMBL105348 | 0.85 | NR1H2 (0.47) | USP2SMN1; SMN2NR1H2MAPK1HPGD | |
| SCHEMBL16843 | 0.85 | NR1H2 (0.47) | USP2SMN1; SMN2NR1H2MAPK1HPGD | |
| SCHEMBL4822309 | 0.84 | USP2 (0.42) | USP2SMN1; SMN2NR1H2MAPK1HPGD | |
| SCHEMBL3561676 | 0.84 | USP2 (0.42) | USP2SMN1; SMN2NR1H2MAPK1HPGD | |
| Urea SCHEMBL4467391 | 0.84 | NR1H2 (0.44) | USP2SMN1; SMN2NR1H2MAPK1HPGD | |
| SCHEMBL18129961 | 0.84 | USP2 (0.42) | USP2SMN1; SMN2NR1H2MAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109096253-B | 2- (4-pyridyl) substituted benzimidazole compound and application of emulsion in water thereof in preventing and treating wheat powdery mildew | 山东农业大学 | 2020-03-31 | — | — | CN | claimed |
| CN-109096253-A | 2-(4- pyridyl group) replace benzimidazoles compound and its aqueous emulsion prevention and treatment wheat powdery mildew in purposes | 山东农业大学 | 2018-12-28 | — | — | CN | claimed |
| CN-109096253-B | 2- (4-pyridyl) substituted benzimidazole compound and application of emulsion in water thereof in preventing and treating wheat powdery mildew | 山东农业大学 | 2020-03-31 | — | — | CN | disclosed |
| CN-109096253-A | 2-(4- pyridyl group) replace benzimidazoles compound and its aqueous emulsion prevention and treatment wheat powdery mildew in purposes | 山东农业大学 | 2018-12-28 | — | — | CN | disclosed |
| US-20040242637-A1 | Tyrosine kinase inhibitors | HARTMAN GEORGE D (US) | 2004-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242637-A1 | Tyrosine kinase inhibitors | ERBB2, TYRO3, TIE1 | USP2 2880/4885SMN1; SMN2 4473/4885NR1H2 1602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.