Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diphenylsulfane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | BCL2 | P10415 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diphenylsulfane SCHEMBL19056221 | 1.00 | HPGD (0.62) | HPGDALDH1A1SIRT1FFAR1MAOA | |
| Diphenylsulfane SCHEMBL7024955 | 1.00 | HPGD (0.62) | HPGDALDH1A1SIRT1FFAR1MAOA | |
| Diphenylsulfane SCHEMBL29264767 | 0.91 | HPGD (0.60) | HPGDALDH1A1SIRT1FFAR1MAOA | |
| Diphenylsulfane SCHEMBL28278324 | 0.88 | SIRT1 (0.59) | HPGDALDH1A1SIRT1FFAR1MAOA | |
| Diphenylsulfane SCHEMBL27619579 | 0.88 | SIRT1 (0.59) | HPGDALDH1A1SIRT1FFAR1MAOA | |
| Diphenylsulfane SCHEMBL27611905 | 0.87 | HPGD (0.60) | HPGDALDH1A1SIRT1MAOAMAOB | |
| Diphenylsulfane SCHEMBL28332331 | 0.87 | HPGD (0.60) | HPGDALDH1A1SIRT1MAOAMAOB | |
| Diphenylsulfane SCHEMBL452 | 0.87 | HPGD (0.60) | HPGDALDH1A1SIRT1MAOAMAOB | |
| Diphenylsulfane SCHEMBL27714827 | 0.87 | HPGD (0.60) | HPGDALDH1A1SIRT1MAOAMAOB | |
| Diphenylsulfane SCHEMBL7109540 | 0.87 | HPGD (0.60) | HPGDALDH1A1SIRT1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110511560-A | A kind of hydrogen gas storage vessel with or hydrogen line Amilan polyamide resin composition | TORAY ADVANCED MATERIALS RES LABORATORIES CHINA CO LTD | 2019-11-29 | — | — | CN | disclosed |
| CN-106573432-B | Surface fastener ring element and hygienic articles | 3M创新有限公司 | 2019-06-28 | — | — | CN | disclosed |
| US-6767624-B2 | SOLID ALUMINUM CONTAINING ELECTROLYTE WITH A FILLER HAVING PARTICLE SIZE OF 1NM-20 MU M AND A POLYMERIC BINDER, AN ADHESION PROMOTING LAYER WITH THICKNESS OF < 100 MU M, AND A COMPONENET WITH ELECTROCHROMIC PROPERTIES | BASF AKTIENGESELLSCHAFT (DE) | 2004-07-27 | — | — | US | disclosed |
| US-20030031858-A1 | Solid aluminum containing electrolyte with a filler having particle size of 1nm-20 mu m and a polymeric binder, an adhesion promoting layer with thickness of < 100 mu m, and a componenet with electrochromic properties | BASF AKTIENGESELLSCHAFT (DE) | 2003-02-13 | — | — | US | disclosed |
| US-6361709-B1 | COMPRISED OF A POLYMERIC BINDER, FILLER, SALT, AND PLASTICIZER; GOOD CONDUCTIVITY AND TRANSPARENCY; FOR USE IN ELECTROCHROMIC GLAZING SYSTEMS | BASF AKTIENGESELLSCHAFT (DE) | 2002-03-26 | — | — | US | disclosed |