Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.50 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | BID | P55957 | 3/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.39 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.39 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.39 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11443810 | 0.98 | LIPG (0.53) | LIPGTHRATHRBNR1H2NR1H3 | |
| SCHEMBL9560122 | 0.98 | LIPG (0.53) | LIPGTHRATHRBNR1H2NR1H3 | |
| SCHEMBL11434972 | 0.98 | LIPG (0.53) | LIPGTHRATHRBNR1H2NR1H3 | |
| SCHEMBL11435762 | 0.98 | LIPG (0.53) | LIPGTHRATHRBNR1H2NR1H3 | |
| SCHEMBL4952213 | 0.94 | CYP3A4 (0.44) | LIPGTHRATHRBNR1H2NR1H3 | |
| SCHEMBL8593874 | 0.86 | MITF (0.36) | LIPGCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL677129 | 0.82 | LIPG (0.52) | LIPGTHRATHRBNR1H2NR1H3 | |
| SCHEMBL15563405 | 0.82 | LIPG (0.52) | LIPGTHRATHRBNR1H2NR1H3 | |
| SCHEMBL11437371 | 0.82 | LIPG (0.45) | LIPGTHRATHRBALOX5PTGS2 | |
| SCHEMBL8493131 | 0.81 | LIPG (0.55) | LIPGTHRATHRBNR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE38425-E1 | ANTICONVULSANTS ADMINISTERED ORALLLY | UNIVERSITY OF SASKATCHEWAN TECHNOLOGIES, INC. (CA) | 2004-02-10 | — | — | US | claimed |
| EP-0836591-B1 | SEMICARBAZONES HAVING CNS ACTIVITY AND PHARMACEUTICAL PREPARATIONS CONTAINING SAME | UNIV SASKATCHEWAN (CA) | 2001-09-26 | — | — | EP | disclosed |
| CN-1062263-C | Semicarbazones having CNS activity and pharmaceutical preparations containing same | UNIV SASKATCHEWAN (CA) | 2001-02-21 | — | — | CN | disclosed |
| CN-1190388-A | Semicarbazones having central nervous system activity and pharmaceutical preparations containing the same | UNIV SASKATCHEWAN (CA) | 1998-08-12 | — | — | CN | disclosed |
| EP-0396827-A1 | 2-Phenylthiobenzylamine dervivatives and acid addition salts thereof | SPOFA Spojené Podniky Pro Zdravotnickou Vyrobu (CS) | 1990-11-14 | — | — | EP | disclosed |
| EP-0396827-A1 | 2-Phenylthiobenzylamine dervivatives and acid addition salts thereof | SPOFA Spojené Podniky Pro Zdravotnickou Vyrobu (CS) | 1990-11-14 | — | — | EP | disclosed |