Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | APAF1 | O14727 | 1/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | MPO | P05164 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | BLM | P54132 | 1/20 | 0.63 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.63 |
| ▸ | DNMT1 | P26358 | 3/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6843792 | 1.00 | SMN1; SMN2 (0.65) | SMN1; SMN2KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL31414630 | 0.90 | SMN1; SMN2 (0.63) | SMN1; SMN2KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL28163928 | 0.89 | KDM4E (0.64) | SMN1; SMN2KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL29457735 | 0.89 | SMN1; SMN2 (0.66) | SMN1; SMN2KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL828693 | 0.87 | SMN1; SMN2 (0.67) | SMN1; SMN2KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL828692 | 0.87 | SMN1; SMN2 (0.67) | SMN1; SMN2KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL3855611 | 0.86 | KDM4E (0.68) | SMN1; SMN2KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL3380280 | 0.86 | SMN1; SMN2 (0.65) | SMN1; SMN2KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL1162356 | 0.86 | SMN1; SMN2 (0.65) | SMN1; SMN2KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL1162357 | 0.86 | SMN1; SMN2 (0.65) | SMN1; SMN2KDM4EMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040259256-A1 | Methods of unnatural amino acid incorporation in mammalian cells | NEURION PHARMACEUTICALS | 2004-12-23 | — | — | US | disclosed |
| WO-2004085463-A2 | METHODS OF UNNATURAL AMINO ACID INCORPORATION IN PROTEINS IN MAMMALIAN CELLS | NEURION PHARMACEUTICALS (US) | 2004-10-07 | — | — | WO | disclosed |