Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CCR6 | P51684 | 1/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | CPB1 | P15086 | 1/20 | 0.47 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.47 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5530644 | 0.99 | TGM2 (0.54) | TGM2HTTKEAP1NFE2L2LMNA | |
| SCHEMBL16789587 | 0.90 | HTT (0.62) | TGM2HTTKEAP1NFE2L2LMNA | |
| SCHEMBL22356684 | 0.90 | HTT (0.65) | TGM2HTTKEAP1NFE2L2LMNA | |
| Hydrochloric Acid SCHEMBL8503422 | 0.89 | TGM2 (0.61) | TGM2HTTKEAP1NFE2L2LMNA | |
| SCHEMBL27814052 | 0.89 | HTT (0.63) | TGM2HTTKEAP1NFE2L2LMNA | |
| SCHEMBL6839361 | 0.88 | TGM2 (0.62) | TGM2HTTKEAP1NFE2L2LMNA | |
| SCHEMBL23728768 | 0.88 | HTT (0.65) | TGM2HTTKEAP1NFE2L2LMNA | |
| SCHEMBL22356685 | 0.88 | HTT (0.65) | TGM2HTTKEAP1NFE2L2LMNA | |
| Hydrochloric Acid SCHEMBL5531602 | 0.87 | TGM2 (0.61) | TGM2HTTKEAP1NFE2L2LMNA | |
| SCHEMBL30958383 | 0.86 | LMNA (0.54) | TGM2HTTKEAP1NFE2L2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0789708-B1 | MULTIFUNCTIONAL MOLECULAR COMPLEXES FOR GENE TRANSFER TO CELLS | WYETH CORP (US) | 2004-11-03 | — | — | EP | claimed |