Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1525906 | 0.85 | CA1 (0.53) | CA1CA2SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL901296 | 0.85 | CA1 (0.53) | CA1CA2SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL9958015 | 0.77 | CA1 (0.48) | CA1CA2SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL6844821 | 0.77 | CA1 (0.48) | CA1CA2SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL7064128 | 0.77 | CA1 (0.61) | CA1CA2SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL9958014 | 0.76 | CA1 (0.47) | CA1CA2SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL13980850 | 0.76 | CA1 (0.56) | CA1CA2SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL1531320 | 0.75 | HTT (0.54) | CA1CA2SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL10469185 | 0.75 | CA1 (0.44) | CA1CA2SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL10469183 | 0.75 | CA1 (0.44) | CA1CA2SMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012085080-A1 | METHOD OF DETECTING A PROTEOLYTIC ENZYME BY MEANS OF GOLD NANOPARTICLES- CATALYZED AMPLIFICATION OF A SIGNAL | UNIVERSITA' DEGLI STUDI DI PADOVA (IT) | 2012-06-28 | — | — | WO | claimed |
| WO-2012085080-A1 | METHOD OF DETECTING A PROTEOLYTIC ENZYME BY MEANS OF GOLD NANOPARTICLES- CATALYZED AMPLIFICATION OF A SIGNAL | UNIVERSITA' DEGLI STUDI DI PADOVA (IT) | 2012-06-28 | — | — | WO | disclosed |
| US-6765104-B1 | Transition metal complexes of n, n',n″trialkyl-cis-1,3,5-triaminocyclohexane and related compositions and methods of synthesis and use | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2004-07-20 | — | — | US | disclosed |
| WO-2001010870-A1 | TRANSITION METAL COMPLEXES OF N,N',N'-TRIALKYL- CIS,CIS-1,3,5-TRIAMINOCYCLOHEXANE AND RELATED COMPOSITIONS AND METHODS OF SYNTHESIS AND USE | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2001-02-15 | — | — | WO | disclosed |