SCHEMBL901296

SCHEMBL901296

CCc1cc([N+](=O)[O-])ccc1OP(=O)(O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.53
CA2 P00918 2/20 0.53
CES2 O00748 1/20 0.45
CES1 P23141 1/20 0.45
ALDH1A1 P00352 6/20 0.44
HPGD P15428 2/20 0.44
LMNA P02545 1/20 0.44
HTT P42858 2/20 0.44
POLB P06746 1/20 0.44
BCHE P06276 1/20 0.43
ACHE P22303 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
AKR1C3 P42330 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.41
NPBWR1 P48145 1/20 0.41
MCHR1 Q99705 1/20 0.41
INPPL1 O15357 3/20 0.41
INPP5A Q14642 3/20 0.41
AKT1 P31749 1/20 0.41
INPP5B P32019 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1525906 1.00 CA1 (0.53) CA1CA2CES2CES1ALDH1A1
SCHEMBL10469185 0.90 CA1 (0.44) CA1CA2CES2CES1ALDH1A1
SCHEMBL10469183 0.90 CA1 (0.44) CA1CA2CES2CES1ALDH1A1
SCHEMBL1525903 0.88 CA1 (0.49) CA1CA2CES2CES1ALDH1A1
SCHEMBL28339773 0.87 ALDH1A1 (0.46) CA1CA2CES2CES1ALDH1A1
SCHEMBL10469182 0.86 HTT (0.45) CA1CA2ALDH1A1HPGDLMNA
SCHEMBL6844822 0.85 CA1 (0.47) CA1CA2CES2CES1ALDH1A1
SCHEMBL9958015 0.83 CA1 (0.48) CA1CA2CES2CES1ALDH1A1
SCHEMBL6844821 0.83 CA1 (0.48) CA1CA2CES2CES1ALDH1A1
SCHEMBL7064128 0.82 CA1 (0.61) CA1CA2CES2CES1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114728009-B Preventing or treating diseases and disorders associated with tissue damage 李晓祥 2024-09-03 CN disclosed
CN-114728009-A Preventing or treating diseases and disorders associated with tissue damage 李晓祥 2022-07-08 CN disclosed
US-20210017402-A1 ANTI-FOULING PAINTS AND COATINGS REACTIVE SURFACES, LTD., LLP (US) 2021-01-21 US disclosed
US-20200354588-A1 ANTI-FOULING PAINTS AND COATINGS REACTIVE SURFACES, LTD., LLP (US) 2020-11-12 US disclosed
US-20200109297-A1 ENZYMATIC ANTIMICROBIAL AND ANTIFOULING COATINGS AND POLYMERIC MATERIALS REACTIVE SURFACES, LTD., LLP (US) 2020-04-09 US disclosed
US-10413769-B2 Paint having cell wall particulate material with a protective organophosphorus esterase REACTIVE SURFACES, LTD., LLP (US) 2019-09-17 US disclosed
CN-109310741-A For preventing and treating organization protection's peptide of disease relevant to tissue damage and obstacle 阿拉伊姆药品公司 2019-02-05 CN disclosed
CN-105517561-A Tissue protective peptides and peptide analogs for the prevention and treatment of diseases and disorders associated with tissue damage ARAIM PHARMACEUTICALS INC 2016-04-20 CN disclosed
US-20150328490-A1 BIOLOGICAL ACTIVE COATING COMPONENTS, COATINGS, AND COATED SURFACES REACTIVE SURFACES, LTD., LLP 2015-11-19 US disclosed
US-20150191607-A1 Anti-fouling Paints and Coatings REACTIVE SURFACES, LTD (US) 2015-07-09 US disclosed
US-20110070376-A1 Anti-fouling Paints & Coatings REACTIVE SURFACES, LTD. (US) 2011-03-24 US disclosed
WO-2011034931-A2 ANTI-FOULING PAINTS AND COATINGS REACTIVE SURFACE, LTD. (US) 2011-03-24 WO disclosed
US-20100248334-A1 Biological active coating components, coatings, and coated surfaces REACTIVE SURFACES, LTD. 2010-09-30 US disclosed
US-20100233146-A1 Coatings and Surface Treatments Having Active Enzymes and Peptides REACTIVE SURFACES, LTD. (US) 2010-09-16 US disclosed
US-20100210745-A1 Molecular Healing of Polymeric Materials, Coatings, Plastics, Elastomers, Composites, Laminates, Adhesives, and Sealants by Active Enzymes REACTIVE SURFACES, LTD. (US) 2010-08-19 US disclosed
WO-2009155115-A2 COATINGS AND SURFACE TREATMENTS HAVING ACTIVE ENZYMES AND PEPTIDES REACTIVE SURFACES, LTD. (US) 2009-12-23 WO disclosed
US-20090238811-A1 Enzymatic Antimicrobial and Antifouling Coatings and Polymeric Materials REACTIVE SURFACES LTD. 2009-09-24 US disclosed
EP-1551927-A1 BIOLOGICAL ACTIVE COATING COMPONENTS, COATINGS, AND COATED SURFACES McDaniel, Steven C. (US) 2005-07-13 EP disclosed
WO-2004112482-A2 BIOLOGICAL ACTIVE COATING COMPONENTS, COATINGS, AND COATED SURFACES MCDANIEL STEVEN C (US) 2004-12-29 WO disclosed
US-20040109853-A1 Detoxification surfaces using phosphoric triester hydrolases REACTIVE SURFACES, LTD. 2004-06-10 US disclosed