Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | INPPL1 | O15357 | 4/20 | 0.40 |
| ▸ | INPP5A | Q14642 | 3/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6844821 | 1.00 | CA1 (0.48) | CA1CA2PKMCES2CES1 | |
| SCHEMBL901296 | 0.83 | CA1 (0.53) | CA1CA2CES2CES1INPPL1 | |
| SCHEMBL1525906 | 0.83 | CA1 (0.53) | CA1CA2CES2CES1INPPL1 | |
| SCHEMBL7064128 | 0.78 | CA1 (0.61) | CA1CA2PKMCES2CES1 | |
| SCHEMBL6844822 | 0.77 | CA1 (0.47) | CA1CA2CES2CES1AKR1C3 | |
| SCHEMBL11325729 | 0.75 | PKM (0.49) | CA1CA2PKMTSHRTDP1 | |
| SCHEMBL6041202 | 0.75 | CA1 (0.57) | CA1CA2CES2CES1INPPL1 | |
| SCHEMBL6041195 | 0.75 | CA1 (0.57) | CA1CA2CES2CES1INPPL1 | |
| SCHEMBL4823831 | 0.74 | CA1 (0.56) | CA1CA2CES2CES1INPPL1 | |
| SCHEMBL4535386 | 0.74 | CA1 (0.56) | CA1CA2PKMCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012085080-A1 | METHOD OF DETECTING A PROTEOLYTIC ENZYME BY MEANS OF GOLD NANOPARTICLES- CATALYZED AMPLIFICATION OF A SIGNAL | UNIVERSITA' DEGLI STUDI DI PADOVA (IT) | 2012-06-28 | — | — | WO | disclosed |