SCHEMBL68449

SCHEMBL68449

O=C(O)c1cc(Cl)c(C(=O)O)cc1Cl

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.61
TSHR P16473 3/20 0.61
TP53 P04637 1/20 0.61
CASP1 P29466 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
CA1 P00915 2/20 0.56
CA2 P00918 2/20 0.56
CA12 O43570 1/20 0.56
CA3 P07451 1/20 0.56
CA4 P22748 1/20 0.56
CA6 P23280 1/20 0.56
CA5A P35218 1/20 0.56
CA7 P43166 1/20 0.56
CA9 Q16790 1/20 0.56
CA13 Q8N1Q1 1/20 0.56
CISD1 Q9NZ45 1/20 0.56
CA14 Q9ULX7 1/20 0.56
CA5B Q9Y2D0 1/20 0.56
AKR1C4 P17516 1/20 0.52
AKR1C3 P42330 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28534088 0.97 ALDH1A1 (0.58) ALDH1A1TSHRTP53CASP1SMN1; SMN2
Hydrochloric Acid SCHEMBL944411 0.97 ALDH1A1 (0.58) ALDH1A1TSHRTP53CASP1SMN1; SMN2
Hydrochloric Acid SCHEMBL5080692 0.97 ALDH1A1 (0.58) ALDH1A1TSHRTP53CASP1SMN1; SMN2
SCHEMBL10825837 0.94 ALDH1A1 (0.56) ALDH1A1TSHRTP53CASP1SMN1; SMN2
SCHEMBL2818580 0.94 CA1 (0.57) ALDH1A1TSHRTP53CASP1SMN1; SMN2
SCHEMBL69107 0.91 CA1 (0.59) ALDH1A1TSHRTP53CASP1SMN1; SMN2
SCHEMBL1154451 0.88 TSHR (0.59) ALDH1A1TSHRTP53CASP1SMN1; SMN2
SCHEMBL30061803 0.87 TSHR (0.56) ALDH1A1TSHRTP53CASP1SMN1; SMN2
SCHEMBL2478971 0.87 TSHR (0.56) ALDH1A1TSHRTP53CASP1SMN1; SMN2
SCHEMBL11680115 0.86 ALDH1A1 (0.54) ALDH1A1TSHRTP53CASP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 778 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120040780-A Method for regulating and controlling luminescence of triphenylamine metal-organic framework material based on mixed ligand strategy 浙江大学 2025-05-27 CN claimed
CN-119708469-A High-strength flame-retardant high-temperature-resistant nylon material and preparation method and application thereof 河北元丰新材料有限公司 2025-03-28 CN claimed
CN-119081104-A Flame-retardant nylon and preparation method thereof 浙江新力新材料股份有限公司 2024-12-06 CN claimed
CN-118994907-A Light-weight high-strength flexible polyarylene sulfide composite material and preparation and application thereof 新凝合科技(成都)有限公司 2024-11-22 CN claimed
WO-2024217376-A1 SEMI-AROMATIC POLYAMIDE RESIN, COMPOSITE MATERIAL, PREPARATION METHOD THEREFOR, AND USE THEREOF 珠海万通特种工程塑料有限公司 2024-10-24 WO claimed
CN-118812862-A Metal-organic framework and rare earth nanocrystalline composite material with thermal enhancement type fluorescence temperature measurement function and preparation method and application thereof 浙江大学杭州国际科创中心 2024-10-22 CN claimed
CN-115873236-B Method and system for preparing high-temperature-resistant nylon by continuous polymerization 浙江新力新材料股份有限公司 2024-08-27 CN claimed
CN-118142356-A Method for preparing ultrathin metal-organic framework film by steam-assisted in-situ conversion and separation application thereof 中国科学院大连化学物理研究所 2024-06-07 CN claimed
CN-117758390-A Benzoxazole-based polymer fiber and preparation method thereof 山东非金属材料研究所 2024-03-26 CN claimed
CN-117306272-A Bio-based PVC leather for automobiles and preparation method thereof 中国第一汽车股份有限公司 2023-12-29 CN claimed
WO-1990007552-A1 BLENDS OF POLY(ETHYLENE TEREPHTHALATE) AND TRANS-4,4'-STILBENEDICARBOXYLIC ACID POLYESTERS EASTMAN KODAK COMPANY (US) 1990-07-12 WO claimed
WO-1990007553-A1 BLENDS OF POLY(ETHYLENE THEREPHTHALATE) AND 4,4'-BIPHENYLDICARBOXYLIC ACID POLYESTERS EASTMAN KODAK COMPANY (US) 1990-07-12 WO claimed
EP-0375575-A1 Blends of poly(ethylene terephthalate) and trans-4,4'-stilbenedicarboxylic acid polyesters EASTMAN KODAK COMPANY (US) 1990-06-27 EP claimed
US-4769441-A Poly(ester-imide-amide of trimellitic anhydride, 4-(aminomethyl)cyclohexanemethanol and aromatic dicarboxylic acid EASTMAN KODAK COMPANY (US) 1988-09-06 US claimed
US-4645802-A MOLDING MATERIALS EASTMAN KODAK COMPANY (US) 1987-02-24 US claimed
US-4554206-A Polyester hot-melt adhesives EASTMAN KODAK COMPANY (US) 1985-11-19 US claimed
US-4468510-A FILMS, FIBERS, MOLDING PLASTICS, LOW GAS PERMEABILITY EASTMAN KODAK COMPANY (US) 1984-08-28 US claimed
US-4101528-A FLAME RETARDANT AVTEX FIBERS INC. (US) 1978-07-18 US claimed
US-4042571-A Fire-retardant polyamides from naphthalene dicarboxylic reactant and halogenated carboxylic reactant TEIJIN LIMITED (JA) 1977-08-16 US claimed
US-3994865-A MELT SPINNING CIBA-GEIGY CORPORATION (US) 1976-11-30 US claimed