Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.65 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1926588 | 1.00 | CTSS (0.65) | CTSSADRB3ADRA2BADRA2CCTSB | |
| SCHEMBL1926454 | 0.95 | CTSS (0.66) | CTSSADRB3ADRA2BADRA2CCTSB | |
| SCHEMBL6844971 | 0.95 | CTSS (0.66) | CTSSADRB3ADRA2BADRA2CCTSB | |
| SCHEMBL6844969 | 0.90 | CTSS (0.69) | CTSSADRB3ADRA2BADRA2CCTSB | |
| SCHEMBL1925451 | 0.90 | CTSS (0.69) | CTSSADRB3ADRA2BADRA2CCTSB | |
| SCHEMBL3054435 | 0.89 | CTSS (0.55) | CTSSADRB3ADRA2BADRA2CCTSB | |
| SCHEMBL3054431 | 0.89 | CTSS (0.55) | CTSSADRB3ADRA2BADRA2CCTSB | |
| SCHEMBL13100634 | 0.89 | CTSS (0.55) | CTSSADRB3ADRA2BADRA2CCTSB | |
| SCHEMBL828774 | 0.87 | CTSS (0.82) | CTSSADRB3ADRA2BADRA2CCTSB | |
| SCHEMBL851151 | 0.87 | CTSS (0.82) | CTSSADRB3ADRA2BADRA2CCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2461811-B1 | MACROCYCLIC SERINE PROTEASE INHIBITORS USEFUL AGAINST VIRAL INFECTIONS, PARTICULARLY HCV | IDENIX PHARMACEUTICALS LLC (US) | 2016-04-20 | — | — | EP | disclosed |
| US-20110129443-A1 | MACROCYCLIC SERINE PROTEASE INHIBITORS | IDENIX PHARMACEUTICALS, INC. (US) | 2011-06-02 | — | — | US | disclosed |
| WO-2011017389-A1 | MACROCYCLIC SERINE PROTEASE INHIBITORS USEFUL AGAINST VIRAL INFECTIONS, PARTICULARLY HCV | IDENIX PHARMACEUTICALS, INC. (US) | 2011-02-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110129443-A1 | MACROCYCLIC SERINE PROTEASE INHIBITORS | SERPINB1, SPINT2, PRSS1 | CTSS 45/4885ADRB3 4357/4885ADRA2B 4030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.