Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL252506 | 1.00 | ALDH1A1 (0.51) | ALDH1A1MAPTL3MBTL1KMT2AMAPK1 | |
| SCHEMBL27456628 | 0.86 | KMT2A (0.48) | ALDH1A1MAPTL3MBTL1KMT2AMAPK1 | |
| SCHEMBL5071027 | 0.81 | ALDH1A1 (0.43) | ALDH1A1MAPTL3MBTL1KMT2AMAPK1 | |
| SCHEMBL11343167 | 0.80 | KHK (0.52) | ALDH1A1MAPTL3MBTL1KMT2AMAPK1 | |
| SCHEMBL27586092 | 0.80 | HDAC2 (0.46) | ALDH1A1MAPTL3MBTL1KMT2AMAPK1 | |
| SCHEMBL9782613 | 0.79 | ITGB1 (0.58) | ALDH1A1MAPTL3MBTL1KMT2AMAPK1 | |
| SCHEMBL3683716 | 0.79 | MAPT (0.51) | ALDH1A1MAPTL3MBTL1KMT2AMAPK1 | |
| SCHEMBL14208954 | 0.79 | MAPT (0.51) | ALDH1A1MAPTL3MBTL1KMT2AMAPK1 | |
| SCHEMBL14178966 | 0.79 | MAPT (0.51) | ALDH1A1MAPTL3MBTL1KMT2AMAPK1 | |
| SCHEMBL7860033 | 0.79 | POLB (0.54) | ALDH1A1MAPTL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011076744-A1 | DISUBSTITUTED HETEROARYL-FUSED PYRIDINES | NOVARTIS AG (CH) | 2011-06-30 | — | — | WO | disclosed |