Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 8/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | QPCT | Q16769 | 1/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | DGAT2 | Q96PD7 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6656515 | 0.87 | CYP17A1 (0.47) | DHODHCYP17A1CYP1A2HSD11B1 | |
| SCHEMBL6661647 | 0.85 | MAPK14 (0.44) | CYP17A1CYP1A2CYP11B1CYP11B2CDC7 | |
| SCHEMBL6657600 | 0.83 | CYP11B1 (0.43) | CYP17A1CYP1A2SLC22A12CYP11B1CYP11B2 | |
| SCHEMBL6661929 | 0.81 | MET (0.42) | CYP1A2QPCTGSK3BMAPT | |
| SCHEMBL6840591 | 0.81 | CYP17A1 (0.52) | CYP17A1CYP1A2 | |
| SCHEMBL6845971 | 0.81 | SETD7 (0.41) | CYP17A1CYP1A2SLC22A12HSD11B1 | |
| SCHEMBL6658314 | 0.80 | MAPT (0.44) | GRIN1GRIN2BCYP17A1CYP11B1CYP11B2 | |
| SCHEMBL6844416 | 0.79 | CDC7 (0.41) | CYP17A1CYP1A2CDC7CDK2 | |
| SCHEMBL6844285 | 0.78 | CYP11B2 (0.42) | CYP17A1CYP1A2SLC22A12CYP11B1CYP11B2 | |
| SCHEMBL6659801 | 0.76 | CYP1A2 (0.40) | GRIN1GRIN2BCYP1A2SLC22A12CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040236110-A1 | Substituted 3-pyridyl indoles and indazoles as c17,20 lyase inhibitors | BAYER PHARMACEUTICALS CORPORATION | 2004-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040236110-A1 | Substituted 3-pyridyl indoles and indazoles as c17,20 lyase inhibitors | CYP17A1, IDO1, CYP21A2 | DHODH 121/4885GRIN1 3702/4885GRIN2B 4156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.