Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 5/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6662653 | 0.92 | POLB (0.40) | CYP11B1CYP11B2CYP19A1CYP3A4S1PR1 | |
| SCHEMBL6660298 | 0.79 | CYP11B2 (0.55) | CYP11B1CYP11B2CYP19A1MKNK1MKNK2 | |
| SCHEMBL6661647 | 0.74 | MAPK14 (0.44) | CYP11B1CYP11B2CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL3892970 | 0.73 | IKBKB (0.56) | CYP11B1CYP11B2CYP19A1CYP3A4MKNK1 | |
| SCHEMBL6654310 | 0.72 | CYP11B1 (0.45) | CYP11B1CYP11B2CYP19A1MAPTCYP1A2 | |
| SCHEMBL23326169 | 0.72 | MKNK1 (0.56) | CYP11B1CYP11B2CYP19A1CYP3A4MKNK1 | |
| SCHEMBL29775379 | 0.72 | MKNK1 (0.56) | CYP11B1CYP11B2CYP19A1CYP3A4MKNK1 | |
| SCHEMBL4506402 | 0.72 | CYP11B1 (0.60) | CYP11B1CYP11B2CYP19A1CYP3A4MKNK1 | |
| SCHEMBL6653590 | 0.72 | CYP11B2 (0.49) | CYP11B1CYP11B2CYP19A1CYP3A4MAPT | |
| SCHEMBL6845462 | 0.72 | MAPT (0.49) | CYP11B1CYP11B2CYP19A1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040236110-A1 | Substituted 3-pyridyl indoles and indazoles as c17,20 lyase inhibitors | BAYER PHARMACEUTICALS CORPORATION | 2004-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040236110-A1 | Substituted 3-pyridyl indoles and indazoles as c17,20 lyase inhibitors | CYP17A1, IDO1, CYP21A2 | CYP11B1 30/4885CYP11B2 53/4885CYP19A1 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.