SCHEMBL684556

SCHEMBL684556

O=C(N/N=C/c1ccccc1O)c1cccc(C(F)(F)F)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 1.00
KDM4E B2RXH2 5/20 1.00
HTT P42858 4/20 1.00
LMNA P02545 3/20 1.00
PTBP1 P26599 2/20 1.00
SMN1; SMN2 Q16637 2/20 1.00
POLB P06746 2/20 1.00
TDP1 Q9NUW8 2/20 1.00
MAPT P10636 5/20 0.68
KDM1A O60341 3/20 0.67
MEN1 O00255 5/20 0.65
HPGD P15428 2/20 0.65
HSP90AA1 P07900 1/20 0.65
GAA P10253 1/20 0.65
ALOX12 P18054 1/20 0.65
DUSP3 P51452 1/20 0.62
PTPN5 P54829 1/20 0.62
PTPN11 Q06124 1/20 0.62
MAOA P21397 1/20 0.60
MAOB P27338 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6571712 1.00 KMT2A (1.00) KMT2AKDM4EHTTLMNAPTBP1
SCHEMBL6571710 1.00 KMT2A (1.00) KMT2AKDM4EHTTLMNAPTBP1
SCHEMBL6568354 0.88 KMT2A (0.78) KMT2AKDM4EHTTLMNAPTBP1
SCHEMBL6568357 0.88 KMT2A (0.78) KMT2AKDM4EHTTLMNAPTBP1
SCHEMBL6571437 0.88 KDM4E (0.78) KMT2AKDM4EHTTLMNAPTBP1
SCHEMBL6571440 0.88 KDM4E (0.78) KMT2AKDM4EHTTLMNAPTBP1
SCHEMBL6749902 0.88 KDM4E (0.78) KMT2AKDM4EHTTLMNAPTBP1
SCHEMBL6749907 0.88 KDM4E (0.78) KMT2AKDM4EHTTLMNAPTBP1
SCHEMBL12746244 0.87 KMT2A (0.77) KMT2AKDM4EHTTLMNAPTBP1
SCHEMBL6569011 0.86 KMT2A (0.75) KMT2AKDM4EHTTLMNAPTBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3524347-A1 USE OF METAL HYDRAZIDE COMPLEX COMPOUNDS AS OXIDATION CATALYSTS BASF SE (DE) 2019-08-14 EP disclosed
EP-2271426-B1 USE OF HYDRAZIDE COMPOUNDS AS OXIDATION CATALYSTS BASF SE (DE) 2019-02-20 EP disclosed
US-8791298-B2 Use of metal hydrazide complex compounds as oxidation catalysts BASF SE (DE) 2014-07-29 US disclosed
US-8791298-B2 Use of metal hydrazide complex compounds as oxidation catalysts BASF SE (DE) 2014-07-29 US disclosed
US-20130281353-A1 Use of Metal Hydrazide Complex Compounds as Oxidation Catalysts BASF SE (DE) 2013-10-24 US disclosed
US-20130281353-A1 Use of Metal Hydrazide Complex Compounds as Oxidation Catalysts BASF SE (DE) 2013-10-24 US disclosed
US-8492324-B2 Use of metal hydrazide complex compounds as oxidation catalysts BASF SE (DE) 2013-07-23 US disclosed
US-8492324-B2 Use of metal hydrazide complex compounds as oxidation catalysts BASF SE (DE) 2013-07-23 US disclosed
US-20120010075-A1 SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER DOW AGROSCIENCES LLC (US) 2012-01-12 US disclosed
US-20120010075-A1 SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER DOW AGROSCIENCES LLC (US) 2012-01-12 US disclosed
US-20110071066-A1 USE OF METAL HYDRAZIDE COMPLEX COMPOUNDS AS OXIDATION CATALYSTS BASF SE (DE) 2011-03-24 US disclosed
US-20110071066-A1 USE OF METAL HYDRAZIDE COMPLEX COMPOUNDS AS OXIDATION CATALYSTS BASF SE (DE) 2011-03-24 US disclosed
WO-2009124855-A1 USE OF METAL HYDRAZIDE COMPLEX COMPOUNDS AS OXIDATION CATALYSTS BASF SE (DE) 2009-10-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110071066-A1 USE OF METAL HYDRAZIDE COMPLEX COMPOUNDS AS OXIDATION CATALYSTS SOD1, H1-4, H1-5 KMT2A 453/4885KDM4E 348/4885HTT 2037/4885
US-20120010075-A1 SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER SOD1, CYP51A1, SOD3 KMT2A 1362/4885KDM4E 1473/4885HTT 386/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.