Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 6/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6844370 | 0.83 | CYP11B1 (0.43) | CYP11B2CYP11B1CYP17A1CYP3A4CYP1A2 | |
| Trifluoroacetic Acid SCHEMBL6657105 | 0.73 | L3MBTL1 (0.46) | CYP11B2CYP11B1CYP19A1MKNK1MKNK2 | |
| SCHEMBL6846192 | 0.69 | CYP2A6 (0.44) | CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6 | |
| SCHEMBL6660298 | 0.69 | CYP11B2 (0.55) | CYP11B2CYP11B1CYP19A1CYP17A1MKNK1 | |
| SCHEMBL15839178 | 0.69 | CYP17A1 (0.45) | CYP11B2CYP11B1CYP17A1MKNK1MKNK2 | |
| SCHEMBL13036623 | 0.69 | CYP2A6 (0.62) | CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6 | |
| SCHEMBL18561787 | 0.67 | CYP11B1 (0.58) | CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6 | |
| SCHEMBL15262718 | 0.66 | CYP2A6 (0.58) | CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6 | |
| SCHEMBL19594479 | 0.66 | CYP2A6 (0.58) | CYP11B2CYP11B1CYP19A1CYP2A6ALDH1A1 | |
| SCHEMBL15984859 | 0.65 | CYP2A6 (0.62) | CYP11B2CYP11B1CYP19A1CYP17A1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040236110-A1 | Substituted 3-pyridyl indoles and indazoles as c17,20 lyase inhibitors | BAYER PHARMACEUTICALS CORPORATION | 2004-11-25 | — | — | US | disclosed |
| US-20040224945-A1 | Novel substituted pyrazole derivatives | BAYER HEALTHCARE AG (DE) | 2004-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040236110-A1 | Substituted 3-pyridyl indoles and indazoles as c17,20 lyase inhibitors | CYP17A1, IDO1, CYP21A2 | CYP11B2 53/4885CYP11B1 30/4885CYP19A1 9/4885 |
| US-20040224945-A1 | Novel substituted pyrazole derivatives | CYP11B2, CYP11B1, ADRB3 | CYP11B2 1/4885CYP11B1 2/4885CYP19A1 896/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.