Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.55 |
| ▸ | CYP11B2 | P19099 | 9/20 | 0.53 |
| ▸ | CYP11B1 | P15538 | 8/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.53 |
| ▸ | CYP17A1 | P05093 | 4/20 | 0.53 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | QPCT | Q16769 | 1/20 | 0.42 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6846114 | 0.93 | HTR1D (0.48) | HTR1DCYP11B2CYP11B1CYP19A1CYP17A1 | |
| SCHEMBL6844272 | 0.90 | HTR6 (0.50) | HTR1DCYP11B2CYP11B1CYP19A1CYP17A1 | |
| SCHEMBL6845970 | 0.88 | HTR1D (0.48) | HTR1DCYP11B2CYP11B1CYP19A1CYP17A1 | |
| SCHEMBL6846125 | 0.88 | CYP11B2 (0.59) | HTR1DCYP11B2CYP11B1CYP19A1CYP17A1 | |
| SCHEMBL6660867 | 0.88 | MAPT (0.46) | HTR1DCYP11B2CYP11B1CYP19A1CYP17A1 | |
| SCHEMBL6659322 | 0.88 | HTR1D (0.47) | HTR1DCYP11B2CYP11B1CYP19A1CYP3A4 | |
| SCHEMBL6658140 | 0.87 | CYP19A1 (0.55) | HTR1DCYP11B2CYP11B1CYP19A1CYP17A1 | |
| SCHEMBL6658742 | 0.85 | CYP11B2 (0.57) | HTR1DCYP11B2CYP11B1CYP19A1CYP17A1 | |
| SCHEMBL6844427 | 0.84 | CYP11B2 (0.54) | HTR1DCYP11B2CYP11B1CYP19A1CYP17A1 | |
| SCHEMBL6846000 | 0.84 | CDC7 (0.43) | HTR1DCYP11B2CYP11B1CYP19A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040236110-A1 | Substituted 3-pyridyl indoles and indazoles as c17,20 lyase inhibitors | BAYER PHARMACEUTICALS CORPORATION | 2004-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040236110-A1 | Substituted 3-pyridyl indoles and indazoles as c17,20 lyase inhibitors | CYP17A1, IDO1, CYP21A2 | HTR1D 1156/4885CYP11B2 53/4885CYP11B1 30/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.