Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 8/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 8/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.49 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.44 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6659873 | 0.90 | CYP11B2 (0.52) | HTR1DCYP11B1CYP11B2CYP19A1CYP17A1 | |
| SCHEMBL6844241 | 0.81 | CYP11B2 (0.49) | HTR1DCYP11B1CYP11B2CYP19A1CYP17A1 | |
| SCHEMBL6846150 | 0.81 | HTR1D (0.55) | HTR1DCYP11B1CYP11B2CYP19A1CYP17A1 | |
| SCHEMBL6845970 | 0.79 | HTR1D (0.48) | HTR1DCYP11B1CYP11B2CYP19A1CYP17A1 | |
| SCHEMBL6846114 | 0.77 | HTR1D (0.48) | HTR1DCYP11B1CYP11B2CYP19A1CYP17A1 | |
| SCHEMBL6658140 | 0.75 | CYP19A1 (0.55) | HTR1DCYP11B1CYP11B2CYP19A1CYP17A1 | |
| SCHEMBL6657245 | 0.74 | CYP11B2 (0.52) | HTR1DCYP11B1CYP11B2CYP19A1CYP17A1 | |
| SCHEMBL5661564 | 0.74 | DOT1L (0.52) | CYP19A1DOT1LCYP2A6 | |
| SCHEMBL6659366 | 0.73 | CYP19A1 (0.47) | CYP11B1CYP11B2CYP19A1DOT1LMAPT | |
| SCHEMBL6845513 | 0.72 | CYP11B2 (0.49) | HTR1DCYP11B1CYP11B2CYP19A1CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040236110-A1 | Substituted 3-pyridyl indoles and indazoles as c17,20 lyase inhibitors | BAYER PHARMACEUTICALS CORPORATION | 2004-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040236110-A1 | Substituted 3-pyridyl indoles and indazoles as c17,20 lyase inhibitors | CYP17A1, IDO1, CYP21A2 | HTR1D 1156/4885CYP11B1 30/4885CYP11B2 53/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.