Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31587903 | 0.77 | CHEK1 (0.62) | CYP1A2CYP2A6PDPK1CHEK1NPC1 | |
| SCHEMBL507331 | 0.77 | CHEK1 (0.62) | CYP1A2CYP2A6PDPK1CHEK1NPC1 | |
| SCHEMBL1210907 | 0.77 | CYP1A2 (0.48) | CYP1A2CYP2A6PDPK1CHEK1NPC1 | |
| Fluoride SCHEMBL28210100 | 0.75 | CHEK1 (0.60) | CYP1A2CYP2A6PDPK1CHEK1NPC1 | |
| SCHEMBL18751056 | 0.73 | CYP1A2 (0.45) | CYP1A2CYP2A6PDPK1CHEK1NPC1 | |
| Anthracene SCHEMBL28212240 | 0.71 | GRM5 (0.46) | CYP1A2KDM4ETDP1 | |
| SCHEMBL22815839 | 0.71 | BACE1 (0.40) | KDM4ETDP1 | |
| SCHEMBL22816512 | 0.69 | TRPA1 (0.40) | CYP1A2NPC1RAB9AKDM4EGPR3 | |
| SCHEMBL6574903 | 0.69 | CYP1A2 (0.54) | CYP1A2CYP2A6PDPK1CHEK1NPC1 | |
| SCHEMBL30092846 | 0.69 | CYP1A2 (0.54) | CYP1A2CYP2A6PDPK1CHEK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040092747-A1 | Amide compounds and pharmaceutical compositions for inhibiting protein kinases, and methods for their use | BENDER STEVEN LEE (US) | 2004-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092747-A1 | Amide compounds and pharmaceutical compositions for inhibiting protein kinases, and methods for their use | BRAF, CNKSR1, UACA | CYP1A2 4207/4885CYP2A6 4078/4885PDPK1 52/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.