⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10599319 | 0.78 | — | — | |
| SCHEMBL8053707 | 0.75 | TSHR (0.43) | — | |
| SCHEMBL130724 | 0.73 | — | — | |
| SCHEMBL17966532 | 0.73 | ALDH1A1 (0.33) | — | |
| SCHEMBL12677850 | 0.72 | TSHR (0.40) | — | |
| SCHEMBL17966474 | 0.67 | — | — | |
| SCHEMBL2103848 | 0.67 | — | — | |
| SCHEMBL17966607 | 0.67 | — | — | |
| SCHEMBL2452193 | 0.67 | — | — | |
| SCHEMBL1931341 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5853808-A | Method of using siloxane polymers | GELEST INC. (US) | 1998-12-29 | — | — | US | claimed |
| CN-107223127-B | Method for producing organohalosilanes | 美国陶氏有机硅公司 | 2020-09-11 | — | — | CN | disclosed |
| EP-3253770-B1 | METHOD OF PRODUCING ORGANOHALOSILANES | DOW SILICONES CORP (US) | 2020-09-02 | — | — | EP | disclosed |
| EP-3253771-B1 | METHOD OF PRODUCING ORGANOHALOSILANES | DOW SILICONES CORP (US) | 2020-08-12 | — | — | EP | disclosed |
| CN-107206355-B | Method for producing organohalosilanes | 美国陶氏有机硅公司 | 2020-07-07 | — | — | CN | disclosed |
| US-10183958-B2 | Method of producing organohalosilanes | DOW SILICONES CORPORATION (US) | 2019-01-22 | — | — | US | disclosed |
| US-20180105542-A1 | Method Of Producing Organohalosilanes | DOW SILICONES CORPORATION | 2018-04-19 | — | — | US | disclosed |
| US-9908903-B2 | Method of producing organohalosilanes | DOW CORNING CORPORATION (US) | 2018-03-06 | — | — | US | disclosed |
| US-20170369514-A1 | Method Of Producing Organohalosilanes | DOW SILICONES CORPORATION | 2017-12-28 | — | — | US | disclosed |
| WO-2016126808-A1 | METHOD OF PRODUCING ORGANOHALOSILANES | DOW CORNING CORPORATION (US) | 2016-08-11 | — | — | WO | disclosed |
| WO-2016126804-A1 | METHOD OF PRODUCING ORGANOHALOSILANES | DOW CORNING CORPORATION (US) | 2016-08-11 | — | — | WO | disclosed |
| US-6770726-B1 | PREPARING SILICA-RICH CERAMIC COATINGS BY HYDROLYSIS AND CONDENSATION OF ORGANOSILANES SUCH AS CHLOROETHYLTRICHLOROSILANE; EVAPORATION, HEATING | GELEST, INC. | 2004-08-03 | — | — | US | disclosed |
| US-5853808-A | Method of using siloxane polymers | GELEST INC. (US) | 1998-12-29 | — | — | US | disclosed |
| WO-1997010282-A1 | BETA-SUBSTITUTED ORGANOSILSESQUIOXANES AND USE THEREOF | GELEST, INC. (US) | 1997-03-20 | — | — | WO | disclosed |
| EP-0135692-B1 | PROCESS FOR THE PREPARATION OF 2-CHLORETHYLDICHLORSILANES | HÜLS AKTIENGESELLSCHAFT (DE) | 1989-01-25 | — | — | EP | disclosed |
| US-4571427-A | REACTING VINYLDICHLOROSILANES AND HYDROGEN CHLORIDE; BY PRODUCT INHIBITION | DYNAMIT NOBEL AG (DE) | 1986-02-18 | — | — | US | disclosed |
| EP-0079043-B1 | PROCESS FOR THE PREPARATION OF 2-CHLOROETHYL SILANES | Wacker-Chemie GmbH (DE) | 1985-08-21 | — | — | EP | disclosed |
| EP-0135692-A2 | Process for the preparation of 2-chlorethyldichlorsilanes | HÜLS AKTIENGESELLSCHAFT (DE) | 1985-04-03 | — | — | EP | disclosed |
| US-4405804-A | Method for preparing 2-chloroethylsilanes | WACKER-CHEMIE GMBH (DE) | 1983-09-20 | — | — | US | disclosed |
| EP-0079043-A1 | Process for the preparation of 2-chloroethyl silanes | Wacker-Chemie GmbH (DE) | 1983-05-18 | — | — | EP | disclosed |