Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11620981 | 0.84 | DCUN1D1 (0.44) | KMT2AIDO1DCUN1D1GAAHTR7 | |
| SCHEMBL8886353 | 0.84 | IDO1 (0.46) | KMT2APOLBHSD11B1IDO1DCUN1D1 | |
| SCHEMBL31310138 | 0.82 | IDO1 (0.44) | KMT2APOLBIDO1DCUN1D1LDHA | |
| SCHEMBL12554990 | 0.81 | KMT2A (0.49) | KMT2APOLBHSD11B1IDO1DCUN1D1 | |
| SCHEMBL11623107 | 0.81 | ALDH1A1 (0.41) | POLBIDO1PTGS2GAAALDH1A1 | |
| SCHEMBL11621636 | 0.79 | DCUN1D1 (0.41) | PTGS1PTGS2DCUN1D1NPC1RAB9A | |
| SCHEMBL11622939 | 0.79 | DCUN1D1 (0.41) | KMT2AHSD11B1IDO1DCUN1D1GAA | |
| SCHEMBL11624648 | 0.79 | DCUN1D1 (0.34) | IDO1DCUN1D1GAAHTR7ALDH1A1 | |
| SCHEMBL11625109 | 0.79 | MBNL1 (0.47) | IDO1DCUN1D1MGAMGAASI | |
| SCHEMBL8883443 | 0.79 | IDO1 (0.42) | KMT2APOLBHSD11B1IDO1DCUN1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130210809-A1 | NOVEL 2-AMINO-4-PYRAZOLYL-THIAZOLE DERIVATIVES AND THEIR USE AS ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | BOLEA CHRISTELLE (CH) | 2013-08-15 | — | — | US | disclosed |
| EP-1021416-B1 | METHOD FOR PRODUCING SUBSTITUTED PYRAZOLES | BASF AG (DE) | 2004-05-19 | — | — | EP | disclosed |
| US-6229022-B1 | REACTING CARBONYL COMPOUNDS WITH HYDRAZINE, ITS HYDRATE OR SALTS IN THE PRESENCE OF SULFURIC ACID AND IODINE OR AN IODINE LIBERATING COMPOUND | BASF AKTIENGESELLSCHAFT (DE) | 2001-05-08 | — | — | US | disclosed |
| EP-1021416-A1 | METHOD FOR PRODUCING SUBSTITUTED PYRAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 2000-07-26 | — | — | EP | disclosed |
| WO-1998058914-A1 | METHOD FOR PRODUCING SUBSTITUTED PYRAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-30 | — | — | WO | disclosed |
| US-4072498-A | HERBICIDES | THE UPJOHN COMPANY (US) | 1978-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130210809-A1 | NOVEL 2-AMINO-4-PYRAZOLYL-THIAZOLE DERIVATIVES AND THEIR USE AS ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | GRM2, GRM4, GRM1 | KMT2A 1336/4885POLB 4484/4885HSD11B1 2655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.