Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CTSV | O60911 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11099515 | 0.80 | ALDH1A1 (0.71) | TP53HTTALDH1A1MAPTKMT2A | |
| SCHEMBL15640142 | 0.79 | LTB4R2 (0.46) | TP53HTTALDH1A1KMT2AMEN1 | |
| SCHEMBL27581466 | 0.79 | TP53 (0.61) | TP53HTTALDH1A1MAPTKMT2A | |
| SCHEMBL4897611 | 0.78 | TP53 (0.47) | TP53HTTALDH1A1GAATSHR | |
| SCHEMBL17064327 | 0.77 | ALDH1A1 (0.56) | HTTALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL3149715 | 0.77 | HTT (1.00) | TP53HTTALDH1A1MAPTKMT2A | |
| SCHEMBL3885646 | 0.75 | ALDH1A1 (1.00) | TP53HTTALDH1A1MAPTKMT2A | |
| SCHEMBL11577825 | 0.75 | ALDH1A1 (0.73) | TP53HTTALDH1A1MAPTKMT2A | |
| SCHEMBL11576314 | 0.75 | ALDH1A1 (0.73) | TP53HTTALDH1A1MAPTKMT2A | |
| SCHEMBL11107017 | 0.74 | ALDH1A1 (0.68) | TP53HTTALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8871463-B2 | Method for screening a glutamate release inhibitor in an astrocyte | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2014-10-28 | — | — | US | disclosed |
| US-20040142891-A1 | Genes involved in immune related responses observed with asthma | UNIVERSITEIT UTRECHT (NL) | 2004-07-22 | — | — | US | disclosed |