Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.34 |
| ▸ | FDPS | P14324 | 4/20 | 0.33 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.32 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.32 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3171638 | 0.85 | LMNA (0.37) | LMNADNM1FDPSSMPD1OPRM1 | |
| SCHEMBL5678037 | 0.85 | LMNA (0.37) | LMNADNM1FDPSSMPD1OPRM1 | |
| SCHEMBL5083185 | 0.83 | LMNA (0.40) | LMNADNM1FDPSSMPD1GPR84 | |
| SCHEMBL1261495 | 0.83 | LMNA (0.40) | LMNADNM1FDPSSMPD1GPR84 | |
| SCHEMBL1261297 | 0.83 | LMNA (0.40) | LMNADNM1FDPSSMPD1GPR84 | |
| SCHEMBL1259447 | 0.83 | LMNA (0.40) | LMNADNM1FDPSSMPD1GPR84 | |
| SCHEMBL11060411 | 0.83 | LMNA (0.40) | LMNADNM1FDPSSMPD1GPR84 | |
| SCHEMBL1260707 | 0.83 | LMNA (0.40) | LMNADNM1FDPSSMPD1GPR84 | |
| SCHEMBL6441868 | 0.83 | DNM1 (0.37) | LMNADNM1FDPSSMPD1OPRM1 | |
| SCHEMBL6847353 | 0.83 | DNM1 (0.37) | LMNADNM1FDPSSMPD1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6770779-B1 | ALKYLATION OF YELLOW PHOSPHORUS WITH ALKYLATING IN BASE TO FORM METAL SALT OF ALKYLPHOSPHONOUS, PHOSPHOROUS AND HYPOPHOSPHOROUS ACIDS; ESTERIFICATION | CLARIANT GMBH (DE) | 2004-08-03 | — | — | US | disclosed |