Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.57 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30062630 | 0.86 | OPRL1 (0.42) | SIGMAR1OPRM1OPRL1OPRD1OPRK1 | |
| SCHEMBL23232266 | 0.86 | OPRL1 (0.42) | SIGMAR1OPRM1OPRL1OPRD1OPRK1 | |
| SCHEMBL4704045 | 0.82 | SIGMAR1 (0.48) | SIGMAR1DRD2OPRM1OPRL1OPRD1 | |
| SCHEMBL4069650 | 0.82 | OPRL1 (0.40) | SIGMAR1OPRM1OPRL1OPRD1OPRK1 | |
| SCHEMBL23649271 | 0.82 | OPRL1 (0.40) | SIGMAR1OPRM1OPRL1OPRD1OPRK1 | |
| SCHEMBL1660350 | 0.82 | SIGMAR1 (0.62) | SIGMAR1DRD2OPRM1HTR2ASLC6A2 | |
| Hydrochloric Acid SCHEMBL10007651 | 0.80 | SIGMAR1 (0.61) | SIGMAR1DRD2OPRM1HTR2ASLC6A2 | |
| SCHEMBL11838166 | 0.80 | PKM (0.41) | SIGMAR1OPRM1OPRL1OPRD1OPRK1 | |
| SCHEMBL27201525 | 0.79 | HTR2A (0.45) | SIGMAR1DRD2OPRM1OPRL1OPRD1 | |
| SCHEMBL8193758 | 0.78 | SIGMAR1 (0.50) | SIGMAR1DRD2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6768024-B1 | CONTROLLING OBESITY, SEXUAL DYSFUNCTION OR INFLAMMATION | LION BIOSCIENCE AG (DE) | 2004-07-27 | — | — | US | disclosed |
| US-4016281-A | Tetralone and indanone compounds | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-04-05 | — | — | US | disclosed |