Hydrogen Sulfide

Hydrogen Sulfide

SCHEMBL6847544

ClCc1ccc(-c2ccccc2)c(-c2ccccc2)c1-c1ccccc1.S

nearest known ligand 0.36

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.36
CYP2A6 P11509 1/20 0.35
CSNK2A1 P68400 2/20 0.34
ALDH1A1 P00352 6/20 0.33
LMNA P02545 2/20 0.33
TSHR P16473 1/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33
CTRC Q99895 2/20 0.32
PDCD1 Q15116 1/20 0.32
CD274 Q9NZQ7 1/20 0.32
ALOX5 P09917 1/20 0.32
BACE1 P56817 1/20 0.32
KMT2A Q03164 1/20 0.32
HDAC4 P56524 1/20 0.31
HDAC2 Q92769 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
HSD17B10 Q99714 2/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphine SCHEMBL996009 0.96 DPP4 (0.36) DPP4CYP2A6CSNK2A1ALDH1A1LMNA
Ammonia Solution, Strong SCHEMBL6848152 0.96 DPP4 (0.36) DPP4CYP2A6CSNK2A1ALDH1A1LMNA
SCHEMBL1930015 0.87 HTT (0.42) DPP4CYP2A6ALDH1A1LMNATSHR
SCHEMBL27522250 0.82 DPP4 (0.47) DPP4CYP2A6ALDH1A1LMNATSHR
Phosphine SCHEMBL7164625 0.80 DPP4 (0.36) DPP4CYP2A6CSNK2A1ALDH1A1LMNA
SCHEMBL29287974 0.78 DHFR (0.41) DPP4LMNAMAPTHTTPDCD1
SCHEMBL608536 0.78 ALDH1A1 (0.50) DPP4CYP2A6ALDH1A1LMNAMAPT
Ammonia Solution, Strong SCHEMBL6847510 0.76 DPP4 (0.36) DPP4CYP2A6CSNK2A1ALDH1A1LMNA
Phosphine SCHEMBL3862243 0.76 DPP4 (0.36) DPP4CYP2A6CSNK2A1ALDH1A1LMNA
Bromide SCHEMBL17106599 0.76 DPP4 (0.36) DPP4CYP2A6CSNK2A1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110293844-A1 PAINT COMPOSITION AND COATING FILM FORMATION METHOD KANSAI PAINT CO., LTD. (JP) 2011-12-01 US disclosed
US-6770694-B2 DRY BLENDING LOWER AND UPPER LAYER-FORMING THERMOSETTING POLYMERS OF SPECIFIC PARTICLE SIZES, OF DIFFERENT MELT VISCOSITIES AND INCLUDING AN ONIUM SALT CURING CATALYST; PROTECTIVE COATINGS; LAYER SEPARATION; WEATHER RESISTANCE KANSAI PAINT CO., LTD. (JP) 2004-08-03 US disclosed
US-20030045613-A1 Powder coating composition for forming multilayer film KANSAI PAINT CO., LTD. (JP) 2003-03-06 US disclosed
EP-1004639-B1 POWDER COATING COMPOSITION FOR FORMING MULTILAYER FILM KANSAI PAINT CO LTD (JP) 2002-11-06 EP disclosed
EP-1004639-A1 POWDER COATING COMPOSITION FOR FORMING MULTILAYER FILM KANSAI PAINT CO., LTD. (JP) 2000-05-31 EP disclosed