SCHEMBL6847560

SCHEMBL6847560

CC(C)(C)CCCCc1cc(CCCCC(C)(C)C)c(O)c(-n2nc3ccc(Cl)cc3n2)c1

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
ACLY P53396 1/20 0.31
RXFP1 Q9HBX9 1/20 0.30
TP53 P04637 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL605640 0.88 NPC1 (0.37) NPC1RAB9AACLY
SCHEMBL4949050 0.86 ADORA3 (0.39) NPC1RAB9AMAPT
SCHEMBL29756256 0.86 ADORA3 (0.39) NPC1RAB9AMAPT
SCHEMBL28335580 0.86 NPC1 (0.40) NPC1RAB9AMAPT
SCHEMBL8422971 0.81 PTGS2 (0.37) NPC1RAB9AACLYTP53
SCHEMBL74880 0.81 NPC1 (0.34) NPC1RAB9ARXFP1MAPT
SCHEMBL74862 0.80 NPC1 (0.35) NPC1RAB9ARXFP1MAPT
SCHEMBL28875559 0.80 TLR8 (0.35) NPC1RAB9ATP53MAPT
SCHEMBL27464195 0.79 NPC1 (0.36) NPC1RAB9ARXFP1MAPT
SCHEMBL4647349 0.77 PTGS2 (0.35) NPC1RAB9AACLYTP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6773626-B2 Liquid crystal and dichroic dye, exhibits an isotropic liquid state by heat and further exhibits homeotropic (colorless) orientation state by application of both heat and electric field; integrated circuit (IC) TOKYO MAGNETIC PRINTING CO., LTD. (JP) 2004-08-10 US disclosed
US-20020076511-A1 Reversible information display medium of liquid crystal type and non-contact IC card utilizing the same TOKYO MAGNETIC PRINTING CO., LTD. (JP) 2002-06-20 US disclosed
EP-1195423-A1 REVERSIBLE INFORMATION DISPLAY MEDIUM OF LIQUID CRYSTAL TYPE AND NONCONTACT IC CARD UTILIZING THE SAME Tokyo Magnetic Printing Co., Ltd. (JP) 2002-04-10 EP disclosed