Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.61 |
| ▸ | RAB9A | P51151 | 8/20 | 0.61 |
| ▸ | MAPT | P10636 | 7/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.61 |
| ▸ | NPC1 | O15118 | 6/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | CD74 | P04233 | 1/20 | 0.61 |
| ▸ | MIF | P14174 | 1/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.47 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10918996 | 0.78 | HDAC1 (0.58) | ALDH1A1RAB9AMAPTKMT2ANPC1 | |
| SCHEMBL2583325 | 0.77 | HDAC1 (0.51) | ALDH1A1RAB9AMAPTKMT2ANPC1 | |
| SCHEMBL11052563 | 0.77 | HDAC1 (0.51) | ALDH1A1RAB9AMAPTKMT2ANPC1 | |
| SCHEMBL8432354 | 0.77 | HDAC1 (0.51) | ALDH1A1RAB9AMAPTKMT2ANPC1 | |
| SCHEMBL6123166 | 0.77 | HDAC1 (0.55) | ALDH1A1RAB9AMAPTKMT2ANPC1 | |
| SCHEMBL2056290 | 0.77 | HDAC1 (0.51) | ALDH1A1RAB9AMAPTKMT2ANPC1 | |
| SCHEMBL1977126 | 0.77 | HDAC1 (0.72) | ALDH1A1RAB9AMAPTKMT2ANPC1 | |
| SCHEMBL14133319 | 0.76 | ALDH1A1 (0.64) | ALDH1A1RAB9AMAPTKMT2ANPC1 | |
| SCHEMBL10916542 | 0.74 | HDAC1 (0.53) | ALDH1A1RAB9AMAPTKMT2ANPC1 | |
| SCHEMBL5656467 | 0.74 | HDAC1 (0.55) | ALDH1A1RAB9AMAPTKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861843-B1 | Fluorescent ionophoric compounds with a cryptand/crown-ether portion and a coumarin portion, their preparation and their use for measuring metal cation concentrations | TERUMO CARDIOVASCULAR SYS (US) | 2004-07-14 | — | — | EP | disclosed |
| EP-0649848-B1 | Cation-sensing composite structure and compounds for use therein | MINNESOTA MINING & MFG (US) | 2003-05-07 | — | — | EP | disclosed |
| CN-1055288-C | Cation-sensitive composite structures and compounds for use therein | MINNESOTA MINING & MFG (US) | 2000-08-09 | — | — | CN | disclosed |
| US-5958782-A | FLUORESCENT IONOPHORIC COMPOUND IS DISCLOSED THAT INCLUDES A COMPLEXING MOIETY, SUCH AS A CRYPTAND OR CROWN-ETHER PORTION, AND A FLUORESCING MOIETY SUCH AS A COUMARIN PORTION | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-09-28 | — | — | US | disclosed |
| EP-0861843-A2 | Fluorescent ionophoric compounds with a cryptand/crown-ether portion and a coumarin portion, their preparation and their use for measuring metal cation concentrations | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-09-02 | — | — | EP | disclosed |
| US-5672567-A | PRE- AND POST-EMERGENCE | ZENECA LIMITED (GB) | 1997-09-30 | — | — | US | disclosed |
| US-5670453-A | PYRAZINEARYL COMPOUND | ZENECA LIMITED (GB) | 1997-09-23 | — | — | US | disclosed |
| EP-0758323-A1 | HERBICIDAL HYDROXYBENZYL-SUBSTITUTED HETEROARYL COMPOUNDS AND DERIVATIVES THEREOF | ZENECA LIMITED (GB) | 1997-02-19 | — | — | EP | disclosed |
| US-5474743-A | A fluorescent ionophoric compound comprising a cryptand portion and a coumarin portion substituted at the 3-position with an electron withdrawing group | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-12-12 | — | — | US | disclosed |
| WO-1995029898-A1 | HERBICIDAL HYDROXYBENZYL-SUBSTITUTED HETEROARYL COMPOUNDS AND DERIVATIVES THEREOF | ZENECA LIMITED (GB) | 1995-11-09 | — | — | WO | disclosed |
| CN-1106407-A | Cation-sensitive composite structures and compounds for use therein | MINNESOTA MINING & MFG (US) | 1995-08-09 | — | — | CN | disclosed |
| EP-0649848-A1 | Cation-sensing composite structure and compounds for use therein | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-04-26 | — | — | EP | disclosed |