Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 4/20 | 0.32 |
| ▸ | EP300 | Q09472 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 2/20 | 0.32 |
| ▸ | TERT | O14746 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6339247 | 0.91 | ALDH1A1 (0.42) | ALDH1A1TSHRTP53 | |
| SCHEMBL7747368 | 0.81 | — | — | |
| SCHEMBL8773549 | 0.80 | MAPT (0.56) | TSHRMAPTABCC4FAAHTERT | |
| SCHEMBL6252970 | 0.80 | FAAH (0.50) | ALDH1A1TP53MAPTABCC4HDAC3 | |
| SCHEMBL6252065 | 0.80 | MAPT (0.56) | TSHRMAPTABCC4FAAHTERT | |
| SCHEMBL6821345 | 0.80 | MAPT (0.56) | TSHRMAPTABCC4FAAHTERT | |
| SCHEMBL6821586 | 0.80 | FAAH (0.50) | ALDH1A1TP53MAPTABCC4HDAC3 | |
| Hydrochloric Acid SCHEMBL6848395 | 0.78 | MAPT (0.54) | TSHRMAPTABCC4FAAHTERT | |
| SCHEMBL9712564 | 0.78 | PAOX (0.46) | ALDH1A1MAPTFAAHEP300TERT | |
| SCHEMBL2154041 | 0.75 | TSHR (0.72) | ALDH1A1TSHRTP53HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661289-B1 | Vinyl carboxamide derivatives as insecticides and acaricides | SYNGENTA PARTICIPATIONS AG (CH) | 2004-03-03 | — | — | EP | disclosed |
| US-5763481-A | PESTICIDES; INSECTICIDES, MITICIDES | NOVARTIS CORPROATION (US) | 1998-06-09 | — | — | US | disclosed |
| US-5545630-A | PESTICIDES | CIBA-GEIGY CORPORATION (US) | 1996-08-13 | — | — | US | disclosed |
| EP-0661289-A1 | Vinyl carboxamide derivatives as insecticides and acaricides | CIBA-GEIGY AG (CH) | 1995-07-05 | — | — | EP | disclosed |
| US-4950666-A | INSECTS, ACARIDS, AND NEMATODES | FMC CORPORATION (US) | 1990-08-21 | — | — | US | disclosed |