Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.78 |
| ▸ | POLB | P06746 | 3/20 | 0.78 |
| ▸ | NPC1 | O15118 | 2/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.68 |
| ▸ | IP6K1 | Q92551 | 12/20 | 0.67 |
| ▸ | IP6K3 | Q96PC2 | 10/20 | 0.67 |
| ▸ | IP6K2 | Q9UHH9 | 10/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10016470 | 0.85 | NPC1 (1.00) | MEN1KMT2APOLBNPC1ALDH1A1 | |
| SCHEMBL4027834 | 0.81 | ALDH1A1 (1.00) | MEN1KMT2APOLBNPC1ALDH1A1 | |
| SCHEMBL10396398 | 0.81 | IP6K1 (1.00) | MEN1KMT2APOLBNPC1ALDH1A1 | |
| SCHEMBL6849379 | 0.81 | MEN1 (0.67) | MEN1KMT2APOLBNPC1ALDH1A1 | |
| SCHEMBL14434145 | 0.79 | IP6K1 (0.78) | MEN1KMT2APOLBNPC1ALDH1A1 | |
| SCHEMBL25989723 | 0.79 | IP6K1 (1.00) | MEN1KMT2APOLBNPC1ALDH1A1 | |
| SCHEMBL26054580 | 0.78 | ALDH1A1 (0.73) | MEN1KMT2APOLBNPC1ALDH1A1 | |
| SCHEMBL25990455 | 0.78 | IP6K1 (1.00) | MEN1KMT2APOLBNPC1ALDH1A1 | |
| SCHEMBL25990059 | 0.78 | IP6K1 (0.78) | MEN1KMT2APOLBNPC1ALDH1A1 | |
| SCHEMBL25990489 | 0.78 | IP6K1 (0.80) | MEN1KMT2APOLBNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2286808-A1 | Cytohesin inhibitors | Rheinische Friedrich-Wilhelms Universität (DE) | 2011-02-23 | — | — | EP | disclosed |