Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.73 |
| ▸ | MEN1 | O00255 | 3/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.73 |
| ▸ | IP6K1 | Q92551 | 13/20 | 0.72 |
| ▸ | IP6K3 | Q96PC2 | 11/20 | 0.72 |
| ▸ | IP6K2 | Q9UHH9 | 11/20 | 0.72 |
| ▸ | TP53 | P04637 | 1/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.72 |
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4027834 | 0.85 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2AKDM4EIP6K1 | |
| SCHEMBL10396398 | 0.84 | IP6K1 (1.00) | ALDH1A1MEN1KMT2AKDM4EIP6K1 | |
| SCHEMBL25989723 | 0.82 | IP6K1 (1.00) | ALDH1A1MEN1KMT2AKDM4EIP6K1 | |
| SCHEMBL14434145 | 0.82 | IP6K1 (0.78) | ALDH1A1MEN1KMT2AKDM4EIP6K1 | |
| SCHEMBL25990455 | 0.81 | IP6K1 (1.00) | ALDH1A1MEN1KMT2AKDM4EIP6K1 | |
| SCHEMBL31105885 | 0.80 | IP6K1 (0.78) | ALDH1A1MEN1KMT2AKDM4EIP6K1 | |
| SCHEMBL25990645 | 0.79 | IP6K1 (0.95) | ALDH1A1MEN1KMT2AKDM4EIP6K1 | |
| SCHEMBL6848397 | 0.78 | MEN1 (0.78) | ALDH1A1MEN1KMT2AKDM4EIP6K1 | |
| SCHEMBL25990489 | 0.78 | IP6K1 (0.80) | ALDH1A1MEN1KMT2AKDM4EIP6K1 | |
| SCHEMBL31105831 | 0.77 | IP6K1 (0.76) | ALDH1A1MEN1KMT2AKDM4EIP6K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11731967-B2 | Inhibitors of TRIM33 and methods of use | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11731967-B2 | Inhibitors of TRIM33 and methods of use | TRIM33, TRIM28, TRIM4 | ALDH1A1 3246/4885MEN1 4215/4885KMT2A 1335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.