SCHEMBL684841

SCHEMBL684841

O=C(N/N=C/c1cc(Br)ccc1O)c1cccc(Cl)c1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 3/20 0.73
KMT2A Q03164 12/20 0.72
KDM4E B2RXH2 10/20 0.72
MEN1 O00255 8/20 0.72
RAB9A P51151 7/20 0.72
HTT P42858 6/20 0.72
LMNA P02545 4/20 0.72
SMN1; SMN2 Q16637 4/20 0.72
POLB P06746 2/20 0.72
PSMD14 O00487 1/20 0.72
MMP2 P08253 1/20 0.72
BLM P54132 1/20 0.72
MAPT P10636 6/20 0.65
ALOX12 P18054 1/20 0.65
NPC1 O15118 5/20 0.65
MITF O75030 3/20 0.65
TDP1 Q9NUW8 2/20 0.65
ASF1A Q9Y294 2/20 0.65
L3MBTL1 Q9Y468 2/20 0.65
KLF5 Q13887 3/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL684842 0.90 KMT2A (0.76) KDM1AKMT2AKDM4EMEN1RAB9A
SCHEMBL6751419 0.90 KDM1A (0.81) KDM1AKMT2AKDM4EMEN1RAB9A
SCHEMBL6751416 0.90 KDM1A (0.81) KDM1AKMT2AKDM4EMEN1RAB9A
SCHEMBL684639 0.90 KDM1A (0.81) KDM1AKMT2AKDM4EMEN1RAB9A
SCHEMBL26974395 0.90 KMT2A (0.70) KDM1AKMT2AKDM4EMEN1RAB9A
SCHEMBL6570173 0.88 KDM1A (0.77) KDM1AKMT2AKDM4EMEN1RAB9A
SCHEMBL6570169 0.88 KDM1A (0.77) KDM1AKMT2AKDM4EMEN1RAB9A
SCHEMBL684525 0.86 KMT2A (0.85) KDM1AKMT2AKDM4EMEN1RAB9A
SCHEMBL30122159 0.86 KMT2A (0.85) KDM1AKMT2AKDM4EMEN1RAB9A
SCHEMBL20446303 0.86 KMT2A (0.85) KDM1AKMT2AKDM4EMEN1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120010075-A1 SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER DOW AGROSCIENCES LLC (US) 2012-01-12 US disclosed
US-20120010075-A1 SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER DOW AGROSCIENCES LLC (US) 2012-01-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120010075-A1 SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER SOD1, CYP51A1, SOD3 KDM1A 484/4885KMT2A 1362/4885KDM4E 1473/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.