Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.73 |
| ▸ | TSHR | P16473 | 2/20 | 0.73 |
| ▸ | SRC | P12931 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL381595 | 0.94 | CYP3A4 (0.83) | CYP3A4TSHRSRCMEN1KMT2A | |
| SCHEMBL35597 | 0.94 | CYP3A4 (0.83) | CYP3A4TSHRSRCMEN1KMT2A | |
| SCHEMBL9657737 | 0.94 | CYP3A4 (0.83) | CYP3A4TSHRSRCMEN1KMT2A | |
| Triphenyl Phosphate SCHEMBL27323542 | 0.94 | CYP3A4 (0.83) | CYP3A4TSHRSRCMEN1KMT2A | |
| Triphenyl Phosphate SCHEMBL4087814 | 0.94 | CYP3A4 (0.83) | CYP3A4TSHRSRCMEN1KMT2A | |
| SCHEMBL28043117 | 0.93 | CYP3A4 (0.68) | CYP3A4TSHRSRCMEN1KMT2A | |
| Phosphoric Acid SCHEMBL7154747 | 0.92 | TSHR (0.86) | CYP3A4TSHRSRCMEN1KMT2A | |
| Toluene SCHEMBL28113409 | 0.90 | TSHR (0.83) | CYP3A4TSHRSRCMEN1KMT2A | |
| Benzene SCHEMBL27257404 | 0.90 | CYP3A4 (0.91) | CYP3A4TSHRSRCMEN1KMT2A | |
| SCHEMBL34999 | 0.89 | CYP3A4 (0.68) | CYP3A4TSHRSRCMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105209546-B | Polyurethane based-polymer composition | 巴斯夫欧洲公司 | 2018-12-28 | — | — | CN | disclosed |
| CN-107531991-A | Resin combination, prepreg, plywood and multilayer printed circuit board | 日立化成株式会社 | 2018-01-02 | — | — | CN | disclosed |
| CN-103958606-B | Poly carbonate resin composition | 第毛织株式会社 | 2016-09-28 | — | — | CN | disclosed |
| US-20040171709-A1 | Vacuum cooled foams | GREAT LAKES CHEMICAL CORPORATION | 2004-09-02 | — | — | US | disclosed |