Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.86 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.86 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Alcohol SCHEMBL27915032 | 0.93 | TSHR (0.91) | TSHRCYP3A4ALDH1A1MAPK1TDP1 | |
| SCHEMBL131412 | 0.93 | TSHR (1.00) | TSHRCYP3A4ALDH1A1MAPK1TDP1 | |
| SCHEMBL21582 | 0.93 | TSHR (1.00) | TSHRCYP3A4ALDH1A1MAPK1TDP1 | |
| SCHEMBL27393883 | 0.93 | TSHR (1.00) | TSHRCYP3A4ALDH1A1MAPK1TDP1 | |
| SCHEMBL10336991 | 0.93 | TSHR (1.00) | TSHRCYP3A4ALDH1A1MAPK1TDP1 | |
| SCHEMBL27371282 | 0.93 | TSHR (1.00) | TSHRCYP3A4ALDH1A1MAPK1TDP1 | |
| Phosphoric Acid SCHEMBL6848420 | 0.92 | CYP3A4 (0.73) | TSHRCYP3A4ALDH1A1MAPK1TDP1 | |
| Water SCHEMBL29287558 | 0.91 | TSHR (0.95) | TSHRCYP3A4ALDH1A1MAPK1TDP1 | |
| SCHEMBL9785893 | 0.91 | CYP3A4 (0.95) | TSHRCYP3A4ALDH1A1MAPK1TDP1 | |
| SCHEMBL8331868 | 0.91 | TSHR (0.95) | TSHRCYP3A4ALDH1A1MAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023074086-A1 | METHOD FOR PRODUCING CALCIUM CARBONATE | 株式会社白石中央研究所 | 2023-05-04 | — | — | WO | disclosed |
| CN-106450232-A | Preparation method and application of novel lithium ion battery cathode material namely ternary phosphate | 武汉理工力强能源有限公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-106318997-A | Efficient preparation and purification method of thio- (seleno-) phosphoric acid cyclic di-nucleotide cGAMP | 聊城市奥润生物医药科技有限公司 | 2017-01-11 | — | — | CN | disclosed |
| CN-103525354-B | Light-curable sealant material composition | ETERNAL CHEMICAL CO.,LTD. (CN) | 2016-02-24 | — | — | CN | disclosed |
| CN-102898962-B | Dual-curing adhesive composition | ETERNAL CHEMICAL CO LTD | 2015-04-29 | — | — | CN | disclosed |
| CN-103525354-A | Light-curable sealant material composition | ETERNAL CHEMICAL CO LTD | 2014-01-22 | — | — | CN | disclosed |
| CN-102153953-B | Photocurable adhesive composition | ETERNAL CHEMICAL CO LTD | 2013-11-13 | — | — | CN | disclosed |
| CN-102898962-A | Dual-curing adhesive composition | ETERNAL CHEMICAL INDUSTRY CO LTD | 2013-01-30 | — | — | CN | disclosed |
| CN-102153953-A | Photocurable adhesive composition | ETERNAL CHEMICAL CO LTD | 2011-08-17 | — | — | CN | disclosed |
| CN-100376630-C | Resin composition for laser welding and molded article | WINTECH POLYMER LTD (JP) | 2008-03-26 | — | — | CN | disclosed |
| CN-1863870-A | Resin composition for laser welding and molded article | WINTECH POLYMER LTD (JP) | 2006-11-15 | — | — | CN | disclosed |
| US-6545073-B1 | Reacted with a basic salt forming compound; also contain carbonization auxiliaries, a metal-containing compound having a carbonization acceleration effect, a comb-like polymer and a filler. | BLOUNT DAVID H (US) | 2003-04-08 | — | — | US | disclosed |
| WO-1980002429-A1 | IMPROVED HOT MELT ADHESIVE COMPOSITION | DU PONT (US) | 1980-11-13 | — | — | WO | disclosed |