SCHEMBL6848445

SCHEMBL6848445

Cl[Si](Cl)(Cl)C(c1ccccc1)C(c1ccccc1)[Si](Cl)(Cl)Cl

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.48
SRC P12931 1/20 0.42
DPP4 P27487 2/20 0.41
F2 P00734 1/20 0.41
SLC6A2 P23975 3/20 0.40
SLC6A4 P31645 3/20 0.40
SLC6A3 Q01959 3/20 0.40
MTOR P42345 1/20 0.40
RAB9A P51151 1/20 0.40
GRM7 Q14831 1/20 0.40
CYP3A4 P08684 1/20 0.39
ALOX15 P16050 1/20 0.39
HTR2A P28223 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38
CYP19A1 P11511 1/20 0.37
CYP2D6 P10635 1/20 0.36
CFTR P13569 1/20 0.36
GOPC Q9HD26 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4453524 1.00 TSHR (0.48) TSHRSRCDPP4F2SLC6A2
SCHEMBL4453526 1.00 TSHR (0.48) TSHRSRCDPP4F2SLC6A2
SCHEMBL20838573 1.00 TSHR (0.48) TSHRSRCDPP4F2SLC6A2
SCHEMBL6847223 0.83 TSHR (0.39) TSHRSRCDPP4TAAR1CYP2D6
SCHEMBL2684593 0.77 TSHR (0.48) TSHRSRCDPP4F2SLC6A2
SCHEMBL4077859 0.74 TSHR (0.52) TSHRSRCDPP4F2SLC6A2
SCHEMBL208902 0.72 TSHR (0.43) TSHRSRCDPP4F2TAAR1
SCHEMBL7795647 0.72 TSHR (0.43) TSHRSRCDPP4F2TAAR1
SCHEMBL28644195 0.71 TSHR (0.48) TSHRSRCDPP4F2SLC6A2
SCHEMBL6765263 0.70 TSHR (0.42) TSHRSRCDPP4F2SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190091663-A1 Polyoxometalates Comprising Noble Metals And Corresponding Metal Clusters EXXONMOBIL CHEMICAL PATENTS INC. 2019-03-28 US disclosed
US-20040082803-A1 Trichlorosilyl groups containing organochlorosilanes and their preparation methods by the double-silylation of olefins with trichlorosilane KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY 2004-04-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040082803-A1 Trichlorosilyl groups containing organochlorosilanes and their preparation methods by the double-silylation of olefins with trichlorosilane CBR1, OXSR1, HCCS TSHR 182/4885SRC 620/4885DPP4 4840/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.