SCHEMBL2684593

SCHEMBL2684593

Cl[Si](Cl)(Cl)C(c1ccccc1)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.48
SRC P12931 1/20 0.42
DPP4 P27487 2/20 0.41
F2 P00734 1/20 0.41
SLC6A2 P23975 3/20 0.40
SLC6A4 P31645 3/20 0.40
SLC6A3 Q01959 3/20 0.40
HTR2A P28223 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38
CYP19A1 P11511 3/20 0.37
CYP2D6 P10635 1/20 0.36
CFTR P13569 1/20 0.36
GOPC Q9HD26 1/20 0.36
HRH1 P35367 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28644195 0.82 TSHR (0.48) TSHRSRCDPP4F2SLC6A2
SCHEMBL29767057 0.78 TSHR (0.43) TSHRDPP4F2SLC6A2SLC6A4
SCHEMBL4453524 0.77 TSHR (0.48) TSHRSRCDPP4F2SLC6A2
SCHEMBL4453526 0.77 TSHR (0.48) TSHRSRCDPP4F2SLC6A2
SCHEMBL20838573 0.77 TSHR (0.48) TSHRSRCDPP4F2SLC6A2
SCHEMBL6848445 0.77 TSHR (0.48) TSHRSRCDPP4F2SLC6A2
SCHEMBL2933123 0.76 TSHR (0.42) TSHRDPP4F2SLC6A2SLC6A4
SCHEMBL4077859 0.74 TSHR (0.52) TSHRSRCDPP4F2SLC6A2
SCHEMBL208902 0.72 TSHR (0.43) TSHRSRCDPP4F2TAAR1
SCHEMBL7795647 0.72 TSHR (0.43) TSHRSRCDPP4F2TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120199798-A Low-cost porous carbon core-shell nanosphere and preparation and application thereof 复旦大学 2025-06-24 CN claimed
CN-113629253-B Porous silicon@carbon core-shell nanosphere for lithium ion battery cathode and preparation and application thereof 复旦大学 2023-07-04 CN claimed
CN-113629253-A Porous silicon @ carbon core-shell nanosphere for lithium ion battery cathode and preparation and application thereof 复旦大学 2021-11-09 CN claimed
CN-120199798-A Low-cost porous carbon core-shell nanosphere and preparation and application thereof 复旦大学 2025-06-24 CN disclosed
CN-113629253-B Porous silicon@carbon core-shell nanosphere for lithium ion battery cathode and preparation and application thereof 复旦大学 2023-07-04 CN disclosed
CN-113629253-A Porous silicon @ carbon core-shell nanosphere for lithium ion battery cathode and preparation and application thereof 复旦大学 2021-11-09 CN disclosed
CN-113480566-A Organic silicon monomer containing diphenylmethane and ultrahigh-refractive-index semiconductor LED packaging material prepared from organic silicon monomer 广州星光有机硅科技有限公司 2021-10-08 CN disclosed
US-10870917-B2 Functionalized foams UCHICAGO ARGONNE, LLC (US) 2020-12-22 US disclosed
US-20180010248-A1 FUNCTIONALIZED FOAMS UCHICAGO ARGONNE, LLC 2018-01-11 US disclosed
CN-102498117-A Organic Chlorosilane And Method For Preparing Same SAMSUNG FINE CHEMICALS CO LTD 2012-06-13 CN disclosed
US-20120114544-A1 ORGANIC CHLOROHYDROSILANE AND METHOD FOR PREPARING THEM SAMSUNG FINE CHEMICALS CO., LTD (KR) 2012-05-10 US disclosed
US-20020082438-A1 PROCESS FOR PREPARING ORGANOCHLOROSILANES BY DEHYDROHALOGENATIVE COUPLING REACTION OF ALKYL HALIDES WITH CHLOROSILANES JUNG IL-NAM (KR) 2002-06-27 US disclosed
US-6392077-B1 DEHYDROHALOGENATION KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2002-05-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120114544-A1 ORGANIC CHLOROHYDROSILANE AND METHOD FOR PREPARING THEM PHPT1, SIK1, SIK2 TSHR 4386/4885SRC 185/4885DPP4 4599/4885
US-20020082438-A1 PROCESS FOR PREPARING ORGANOCHLOROSILANES BY DEHYDROHALOGENATIVE COUPLING REACTION OF ALKYL HALIDES WITH CHLOROSILANES RCC1, RER1, RIF1 TSHR 1815/4885SRC 434/4885DPP4 4427/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.