SCHEMBL6848448

SCHEMBL6848448

COC(=O)c1ccc(NC(=O)c2cc(-c3ccc(C(=O)O)c(C(=O)O)c3)ccc2C(=O)Nc2cccc(C(=O)OC)c2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.57
PTPN1 P18031 1/20 0.56
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
PPARA Q07869 1/20 0.55
GPR35 Q9HC97 1/20 0.55
PLAU P00749 7/20 0.55
TP53 P04637 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
PLAT P00750 2/20 0.50
NPC1 O15118 2/20 0.50
PLG P00747 1/20 0.50
MAPT P10636 1/20 0.50
ALDH1A1 P00352 1/20 0.50
PKM P14618 1/20 0.50
HPGD P15428 1/20 0.50
MAPK1 P28482 1/20 0.50
GALK1 P51570 1/20 0.49
CASP6 P55212 1/20 0.49
MCL1 Q07820 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6855096 0.97 RAB9A (0.56) RAB9APTPN1MEN1KMT2APPARA
SCHEMBL6852748 0.95 RAB9A (0.63) RAB9AMEN1KMT2APLAUTP53
SCHEMBL6852938 0.95 RAB9A (0.63) RAB9AMEN1KMT2APLAUTP53
SCHEMBL6852588 0.93 RAB9A (0.60) RAB9AMEN1KMT2APPARAGPR35
SCHEMBL6852686 0.93 RAB9A (0.66) RAB9AMEN1KMT2APLAUTP53
SCHEMBL6853182 0.92 PTPN1 (0.58) RAB9APTPN1MEN1KMT2APLAU
SCHEMBL6852426 0.92 PTPN1 (0.58) RAB9APTPN1MEN1KMT2APLAU
SCHEMBL6852756 0.89 PTPN1 (0.61) RAB9APTPN1MEN1KMT2APLAU
SCHEMBL6855624 0.87 HPSE (0.59) RAB9APTPN1MEN1KMT2APPARA
SCHEMBL9164932 0.85 RAB9A (0.73) RAB9AMEN1KMT2ATP53SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6828408-B2 Small coefficient of linear expansion and small water absorbing property, and excellent heat resistance; thermotropic liquid crystalline polymer for engineering plastics SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-07 US disclosed
US-20030083459-A1 Aromatic polyimide ester and method for producing thereof SUMITOMO CHEMICAL COMPANY, LIMITED 2003-05-01 US disclosed