SCHEMBL6853182

SCHEMBL6853182

COC(=O)c1ccc(NC(=O)c2ccc(-c3ccc(C(=O)O)c(C(=O)Nc4ccc(C(=O)OC)cc4)c3)cc2C(=O)O)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.58
MEN1 O00255 5/20 0.51
KMT2A Q03164 5/20 0.51
RAB9A P51151 4/20 0.50
SMN1; SMN2 Q16637 4/20 0.50
NPC1 O15118 3/20 0.50
PLAU P00749 2/20 0.50
ATM Q13315 1/20 0.50
IKBKE Q14164 1/20 0.50
TBK1 Q9UHD2 1/20 0.50
GAA P10253 1/20 0.50
CASP3 P42574 1/20 0.49
SENP7 Q9BQF6 1/20 0.49
MAPT P10636 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
ALDH1A1 P00352 2/20 0.48
HPGD P15428 2/20 0.48
GFER P55789 1/20 0.48
TP53 P04637 1/20 0.48
PKM P14618 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6852426 1.00 PTPN1 (0.58) PTPN1MEN1KMT2ARAB9ASMN1; SMN2
SCHEMBL6852756 0.97 PTPN1 (0.61) PTPN1MEN1KMT2ARAB9ASMN1; SMN2
SCHEMBL6848448 0.92 RAB9A (0.57) PTPN1MEN1KMT2ARAB9ASMN1; SMN2
SCHEMBL9162727 0.89 PTPN1 (0.59) PTPN1MEN1KMT2ARAB9ASMN1; SMN2
SCHEMBL9156996 0.89 PTPN1 (0.59) PTPN1MEN1KMT2ARAB9ASMN1; SMN2
SCHEMBL6855096 0.88 RAB9A (0.56) PTPN1MEN1KMT2ARAB9ASMN1; SMN2
SCHEMBL6852976 0.87 SMN1; SMN2 (0.59) MEN1KMT2ARAB9ASMN1; SMN2NPC1
SCHEMBL6848464 0.87 ALDH1A1 (0.53) PTPN1MEN1KMT2ARAB9ASMN1; SMN2
SCHEMBL6852760 0.87 ALDH1A1 (0.53) PTPN1MEN1KMT2ARAB9ASMN1; SMN2
SCHEMBL6852748 0.86 RAB9A (0.63) MEN1KMT2ARAB9ASMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6828408-B2 Small coefficient of linear expansion and small water absorbing property, and excellent heat resistance; thermotropic liquid crystalline polymer for engineering plastics SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-07 US disclosed
US-20030083459-A1 Aromatic polyimide ester and method for producing thereof SUMITOMO CHEMICAL COMPANY, LIMITED 2003-05-01 US disclosed