Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.69 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | FLT3 | P36888 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28266071 | 0.86 | PTGS1 (0.67) | PTGS2PTGS1ALDH1A1SMN1; SMN2CA12 | |
| SCHEMBL410896 | 0.79 | PTGS1 (0.59) | PTGS2PTGS1ALDH1A1SMN1; SMN2CA12 | |
| SCHEMBL3760446 | 0.79 | TSHR (0.71) | PTGS2PTGS1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL11904310 | 0.79 | TSHR (0.71) | PTGS2PTGS1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL411117 | 0.78 | ALDH1A1 (0.67) | PTGS2PTGS1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL406868 | 0.78 | PTGS1 (0.57) | PTGS2PTGS1ALDH1A1SMN1; SMN2CA12 | |
| SCHEMBL411865 | 0.77 | PTGS1 (0.56) | PTGS2PTGS1ALDH1A1SMN1; SMN2CA12 | |
| SCHEMBL8291470 | 0.77 | PTGS2 (0.68) | PTGS2PTGS1ALDH1A1SMN1; SMN2CA9 | |
| SCHEMBL410493 | 0.76 | PTGS1 (0.58) | PTGS2PTGS1ALDH1A1SMN1; SMN2CA12 | |
| SCHEMBL413774 | 0.76 | CA12 (0.63) | PTGS2PTGS1ALDH1A1SMN1; SMN2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011020849-A1 | CYTOHESIN INHIBITORS | RHEINISCHE FRIEDRICH-WILHELMS UNIVERSITÄT (DE) | 2011-02-24 | — | — | WO | disclosed |
| EP-2286808-A1 | Cytohesin inhibitors | Rheinische Friedrich-Wilhelms Universität (DE) | 2011-02-23 | — | — | EP | disclosed |