Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.37 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6846057 | 0.82 | ESR1 (0.45) | HIF1AMEN1SLC22A1USP2LMNA | |
| SCHEMBL27694968 | 0.74 | ESR2 (0.52) | MAPTHPGDCYP2C9CYP2C19ESR2 | |
| SCHEMBL6846058 | 0.72 | ESR2 (0.55) | HIF1AMEN1SLC22A1USP2LMNA | |
| SCHEMBL4438908 | 0.71 | CCR2 (0.43) | MEN1LMNAMAPTHPGDHTT | |
| SCHEMBL11476243 | 0.71 | ESR1 (0.41) | ALOX12ESR2ESR1OPRD1SLC6A4 | |
| SCHEMBL19114397 | 0.71 | GABRA1 (0.47) | MEN1LMNAMAPTHPGDHTT | |
| SCHEMBL11372671 | 0.69 | CETP (0.36) | HSP90AA1ALOX12CETPESR2OPRD1 | |
| SCHEMBL4442529 | 0.69 | MAOB (0.39) | MAPTKMT2ASLC6A4SLC6A3 | |
| SCHEMBL10064891 | 0.68 | ESR2 (0.49) | MEN1KMT2APTPN1ESR2ESR1 | |
| SCHEMBL4444659 | 0.68 | HRH3 (0.37) | OPRD1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6767949-B1 | REDUCING AGENT COMPRISING PHOSPHORUS COMPOUND, SULFUR COMPOUND OR ETHYLENICALLY UNSATURATED CYCLIC COMPOUND; DISCOLORATION INHIBITION | CIBA SPECIALTY CHEMICALS CORPORATION | 2004-07-27 | — | — | US | disclosed |
| US-6028131-A | Antioxidants containing phenol groups and aromatic amine groups | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-02-22 | — | — | US | disclosed |