Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2602140 | 0.75 | CYP2C19 (0.50) | CYP2C19 | |
| SCHEMBL10455724 | 0.72 | CYP2C19 (0.47) | CYP2C19 | |
| SCHEMBL29046149 | 0.72 | CYP2C19 (0.47) | CYP2C19 | |
| SCHEMBL9998921 | 0.67 | — | — | |
| SCHEMBL1100011 | 0.65 | — | — | |
| SCHEMBL29283618 | 0.64 | CYP2C19 (0.40) | CYP2C19 | |
| SCHEMBL10454809 | 0.61 | — | — | |
| SCHEMBL20079635 | 0.61 | — | — | |
| SCHEMBL21910739 | 0.60 | — | — | |
| SCHEMBL18850533 | 0.59 | ALDH1A1 (0.37) | CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3468954-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BioMarin Pharmaceutical Inc. (US) | 2019-04-17 | — | — | EP | disclosed |
| WO-2017214505-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2017-12-14 | — | — | WO | disclosed |
| EP-2457923-B1 | STEROL DERIVATIVE | KYOWA HAKKO KIRIN CO LTD (JP) | 2016-01-27 | — | — | EP | disclosed |
| US-20150119585-A1 | STEROL DERIVATIVE | KYOWA HAKKO KIRIN CO., LTD (JP) | 2015-04-30 | — | — | US | disclosed |
| US-20150119585-A1 | STEROL DERIVATIVE | KYOWA HAKKO KIRIN CO., LTD (JP) | 2015-04-30 | — | — | US | disclosed |
| US-8952003-B2 | Sterol derivative | KYOWA HAKKO KIRIN CO., LTD (JP) | 2015-02-10 | — | — | US | disclosed |
| US-8952003-B2 | Sterol derivative | KYOWA HAKKO KIRIN CO., LTD (JP) | 2015-02-10 | — | — | US | disclosed |
| US-20120172348-A1 | STEROL DERIVATIVE | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2012-07-05 | — | — | US | disclosed |
| US-20120172348-A1 | STEROL DERIVATIVE | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2012-07-05 | — | — | US | disclosed |
| EP-2457923-A1 | STEROL DERIVATIVE | Kyowa Hakko Kirin Co., Ltd. (JP) | 2012-05-30 | — | — | EP | disclosed |
| WO-2011010682-A1 | STEROL DERIVATIVE | 協和発酵キリン株式会社 (JP) | 2011-01-27 | — | — | WO | disclosed |
| US-20090093638-A1 | Allylic Oxidations Catalyzed by Dirhodium Catalysts under Aqueous Conditions | UNIVERSITY OF MARYLAND, COLLEGE PARK (US) | 2009-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120172348-A1 | STEROL DERIVATIVE | NR1H3, NR1H2, SREBF1 | CYP2C19 2665/4885 |
| US-20150119585-A1 | STEROL DERIVATIVE | NR1H3, NR1H2, SREBF1 | CYP2C19 2665/4885 |
| US-20090093638-A1 | Allylic Oxidations Catalyzed by Dirhodium Catalysts under Aqueous Conditions | CYP11B2, DHCR7, ZDHHC7 | CYP2C19 934/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.