SCHEMBL6850127

SCHEMBL6850127

CN(C)C(C=O)(Cc1ccccc1)Cc1ccc(N2CCOCC2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RORC P51449 5/20 0.46
SMN1; SMN2 Q16637 2/20 0.44
LMNA P02545 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
MAPT P10636 4/20 0.43
TSHR P16473 2/20 0.43
PKM P14618 1/20 0.43
ADRA2A P08913 1/20 0.41
ADRA2B P18089 1/20 0.41
ADRA2C P18825 1/20 0.41
TMEM97 Q5BJF2 1/20 0.41
SIGMAR1 Q99720 1/20 0.41
RAB9A P51151 2/20 0.41
ALOX12 P18054 1/20 0.41
ALDH1A1 P00352 2/20 0.41
KDM4E B2RXH2 1/20 0.41
NPC1 O15118 1/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
POLB P06746 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL123209 0.92 SLC13A5 (0.46) RORCSMN1; SMN2LMNAL3MBTL1MAPT
SCHEMBL20141616 0.92 SLC13A5 (0.46) RORCSMN1; SMN2LMNAL3MBTL1MAPT
SCHEMBL20603021 0.89 SLC13A5 (0.44) RORCSMN1; SMN2L3MBTL1MAPTAOC3
SCHEMBL5573814 0.84 AGXT (0.44) RORCSMN1; SMN2LMNAL3MBTL1MAPT
SCHEMBL3518177 0.83 SLC13A5 (0.46) RORCSMN1; SMN2LMNAL3MBTL1MAPT
SCHEMBL21271600 0.82 RORC (0.44) RORCSMN1; SMN2LMNAL3MBTL1MAPT
SCHEMBL20604076 0.82 NPC1 (0.48) SMN1; SMN2LMNAL3MBTL1MAPTPKM
SCHEMBL2583585 0.82 NPC1 (0.48) SMN1; SMN2LMNAL3MBTL1MAPTPKM
SCHEMBL23927228 0.82 SLC13A5 (0.45) SMN1; SMN2LMNAL3MBTL1MAPTRAB9A
SCHEMBL28498596 0.81 MAPT (0.44) RORCSMN1; SMN2LMNAL3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014153053-A1 WALL CONSTRUCTION BASF CORPORATION (US) 2014-09-25 WO disclosed
WO-2012138844-A2 NON-AQUEOUS ELECTROLYTES FOR LITHIUM-AIR BATTERIES UCHICAGO ARGONNE, LLC (US) 2012-10-11 WO disclosed
US-6777459-B2 CONTAIN ONE OR MORE LIGHTFAST RED, BLUE OR VIOLET ORGANIC PIGMENTS; LOW YELLOW COLOR FORMATION RESULTS UPON CURING ETHENICALLY UNSATURATED COMPOUNDS; USE IN CLEAR OR WHITE COATINGS, SCREEN INKS, POWDER COATINGS, LENSES CIBA SPECIALTY CHEMICALS CORPORATION 2004-08-17 US disclosed
EP-1106627-B1 Novel phosphine oxide photoinitiator systems and curable compositions with low color CIBA SC HOLDING AG (CH) 2003-10-29 EP disclosed
US-20030119932-A1 Novel phosphine oxide photoinitiator systems and curable compostions with low color AL-AKHDAR WALID (US) 2003-06-26 US disclosed
US-6486226-B2 ACYLPHOSPHINE OXIDE PHOTOINITIATOR(S); LIGHTFAST RED, BLUE OR VIOLET ORGANIC PIGMENT(S); UNSATURATED CURABLE COMPOUND(S); CLEAR AND WHITE COATINGS, SCREEN INKS, GEL COATS, POWDER COATINGS, COMPOSITES, ADHESIVES AND LENSES CIBA SPECIALTY CHEMICALS CORPORATION 2002-11-26 US disclosed
US-20020107298-A1 Novel phosphine oxide photoinitiator systems and curable compositions with low color CIBA SPECIALTY CHEMICALS CORP. 2002-08-08 US disclosed
EP-1106627-A1 Novel phosphine oxide photoinitiator systems and curable compositions with low color Ciba SC Holding AG (CH) 2001-06-13 EP disclosed
US-5534559-A UNSATURATED POLYESTERS CIBA-GEIGY CORPORATION (US) 1996-07-09 US disclosed
EP-0615980-A2 Curing of compositions containing Bisacylphosphinoxide CIBA-GEIGY AG (CH) 1994-09-21 EP disclosed