Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6850155 | 0.80 | KDM4E (0.37) | KDM4EUSP2HPGDNPSR1HSD17B10 | |
| SCHEMBL8481385 | 0.70 | NOTUM (0.33) | KDM4EUSP2HPGDNPSR1HSD17B10 | |
| SCHEMBL6764669 | 0.68 | NOTUM (0.38) | KDM4EUSP2HPGDNPSR1HSD17B10 | |
| SCHEMBL6771029 | 0.60 | TP53 (0.39) | KDM4EOPRM1 | |
| SCHEMBL8481634 | 0.60 | KDM4E (0.36) | KDM4EUSP2HPGDNPSR1HSD17B10 | |
| SCHEMBL29044106 | 0.58 | HRH3 (0.48) | — | |
| SCHEMBL3557685 | 0.56 | KDM4E (0.52) | KDM4EUSP2HPGDNPSR1HSD17B10 | |
| SCHEMBL8703450 | 0.56 | TAS1R3 (0.40) | HPGDNPSR1NOTUMEPHX2MEN1 | |
| SCHEMBL5010587 | 0.55 | HTT (0.56) | HTTKMT2A | |
| SCHEMBL46774 | 0.55 | ALDH1A1 (0.55) | KDM4EUSP2HPGDNPSR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774133-B2 | Substituted spiroheterocyclic 1H-3-aryl-pyrrolidine-2,4-dione derivatives, processes for their preparation, and their use as pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 2004-08-10 | — | — | US | disclosed |
| US-6555567-B1 | 2-oxo-3-aryl-4-hydroxy-1-aza-8-thiaspiro(4.5)decane derivatives of given formula; use as arthropodicide or nematicide | BAYER AKTIENGESELLSCHAFT (DE) | 2003-04-29 | — | — | US | disclosed |
| US-6479489-B1 | AN ARTHROPODICIDAL OR NEMATICIDAL COMPOSITION | BAYER AKTIENGESELLSCHAFT (DE) | 2002-11-12 | — | — | US | disclosed |