Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 11/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3184514 | 0.89 | VDR (0.52) | VDR | |
| SCHEMBL14569115 | 0.89 | VDR (0.51) | VDRHDAC6 | |
| SCHEMBL6850730 | 0.88 | VDR (0.49) | VDRHDAC3HDAC6HDAC2 | |
| SCHEMBL6846411 | 0.88 | VDR (0.49) | VDRHDAC3HDAC6HDAC2 | |
| SCHEMBL3187854 | 0.88 | VDR (0.48) | VDRHDAC3HDAC6HDAC2 | |
| SCHEMBL6849332 | 0.88 | VDR (0.48) | VDRHDAC3HDAC6HDAC2 | |
| SCHEMBL3179666 | 0.87 | VDR (0.48) | VDRHDAC3HDAC6HDAC2 | |
| SCHEMBL26326335 | 0.87 | VDR (0.48) | VDRHDAC3HDAC6HDAC2 | |
| SCHEMBL8063708 | 0.87 | VDR (0.48) | VDRHDAC3HDAC6HDAC2 | |
| SCHEMBL3186188 | 0.87 | VDR (0.51) | VDRHDAC3HDAC6HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805682-B1 | DERMATOLOGICAL USE OF VITAMIN D DERIVATIVES | BASILEA PHARMACEUTICA AG (CH) | 2004-08-11 | — | — | EP | disclosed |
| US-5827883-A | TOPICAL DRUG DELIVERY; SIDE EFFECT REDUCTION | HOFFMANN-LA ROCHE INC. (US) | 1998-10-27 | — | — | US | disclosed |