Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 20/20 | 0.64 |
| ▸ | PRSS1 | P07477 | 11/20 | 0.57 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.56 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.56 |
| ▸ | F10 | P00742 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7737354 | 0.89 | F2 (0.54) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL6846379 | 0.84 | F2 (0.65) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL4432108 | 0.82 | F2 (0.77) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL8366434 | 0.81 | F2 (0.74) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL6850170 | 0.81 | F2 (0.61) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL4421701 | 0.81 | F2 (0.73) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL8364629 | 0.80 | F2 (0.56) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL6852033 | 0.78 | KAT2B (0.56) | F2PRSS1 | |
| SCHEMBL6850665 | 0.76 | F2 (0.55) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL7309269 | 0.74 | F2 (0.59) | F2PRSS1PRSS2PRSS3F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6777431-B2 | ANTICOAGULANTS | CORVAS INTERNATIONAL, INC. | 2004-08-17 | — | — | US | disclosed |
| US-6777431-B2 | ANTICOAGULANTS | CORVAS INTERNATIONAL, INC. | 2004-08-17 | — | — | US | disclosed |
| US-6777431-B2 | ANTICOAGULANTS | CORVAS INTERNATIONAL, INC. | 2004-08-17 | — | — | US | disclosed |
| US-20030092679-A1 | Novel non-convalent thrombin inhibitors | DENDREON PHARMACEUTICALS LLC | 2003-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030092679-A1 | Novel non-convalent thrombin inhibitors | F2, SERPINC1, F2RL3 | F2 1/4885PRSS1 26/4885PRSS2 71/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.