Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19198716 | 0.76 | ALDH1A1 (0.39) | SMN1; SMN2HSD17B10ALDH1A1TRPA1 | |
| SCHEMBL9493851 | 0.73 | ALDH1A1 (0.36) | MAPTHTTSMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL9365658 | 0.72 | ALDH1A1 (0.34) | MAPTHTTSMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL4613459 | 0.71 | ALDH1A1 (0.50) | HSD17B10ALDH1A1TRPA1 | |
| SCHEMBL6848284 | 0.70 | TDP1 (0.45) | MAPTALDH1A1 | |
| SCHEMBL20473354 | 0.70 | ALDH1A1 (0.40) | HTTHSD17B10ALDH1A1TRPA1 | |
| SCHEMBL8164787 | 0.69 | ALDH1A1 (0.36) | MAPTHSD17B10ALDH1A1 | |
| SCHEMBL30411265 | 0.69 | ALDH1A1 (0.48) | HSD17B10ALDH1A1TRPA1 | |
| SCHEMBL25376940 | 0.69 | ALDH1A1 (0.39) | HSD17B10ALDH1A1TRPA1 | |
| SCHEMBL25415857 | 0.68 | ALDH1A1 (0.42) | HSD17B10ALDH1A1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661289-B1 | Vinyl carboxamide derivatives as insecticides and acaricides | SYNGENTA PARTICIPATIONS AG (CH) | 2004-03-03 | — | — | EP | disclosed |
| US-5763481-A | PESTICIDES; INSECTICIDES, MITICIDES | NOVARTIS CORPROATION (US) | 1998-06-09 | — | — | US | disclosed |
| US-5545630-A | PESTICIDES | CIBA-GEIGY CORPORATION (US) | 1996-08-13 | — | — | US | disclosed |
| EP-0661289-A1 | Vinyl carboxamide derivatives as insecticides and acaricides | CIBA-GEIGY AG (CH) | 1995-07-05 | — | — | EP | disclosed |