Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNPH1 | O43598 | 1/20 | 0.50 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.44 |
| ▸ | P2RY6 | Q15077 | 9/20 | 0.42 |
| ▸ | P2RY14 | Q15391 | 6/20 | 0.42 |
| ▸ | NT5E | P21589 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5668666 | 0.90 | P2RY2 (0.44) | DNPH1P2RY2P2RY6P2RY14NT5E | |
| SCHEMBL8171833 | 0.89 | DNPH1 (0.41) | DNPH1 | |
| SCHEMBL8171834 | 0.89 | DNPH1 (0.41) | DNPH1 | |
| SCHEMBL7811414 | 0.88 | P2RY6 (0.54) | DNPH1P2RY2P2RY6P2RY14NT5E | |
| SCHEMBL7901418 | 0.87 | DNPH1 (0.38) | DNPH1 | |
| SCHEMBL7901416 | 0.87 | DNPH1 (0.38) | DNPH1 | |
| SCHEMBL10645210 | 0.86 | DNPH1 (0.41) | DNPH1NT5E | |
| SCHEMBL10647159 | 0.86 | DNPH1 (0.41) | DNPH1NT5E | |
| SCHEMBL10645235 | 0.85 | DNPH1 (0.41) | DNPH1P2RY2P2RY6P2RY14NT5E | |
| SCHEMBL10643486 | 0.85 | DNPH1 (0.41) | DNPH1P2RY2P2RY6P2RY14NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465905-A2 | ANTISENSE MODULATION OF MYD88 EXPRESSION | ISIS PHARMACEUTICALS, INC. (US) | 2004-10-13 | — | — | EP | disclosed |
| EP-1328536-A1 | ANTISENSE MODULATION OF GLIOMA-ASSOCIATED ONCOGENE-1 EXPRESSION | ISIS PHARMACEUTICALS, INC. (US) | 2003-07-23 | — | — | EP | disclosed |
| WO-2003049691-A2 | ANTISENSE MODULATION OF PCTAIRE PROTEIN KINASE 1 EXPRESSION | ISIS PHARMACEUTICALS, INC. (US) | 2003-06-19 | — | — | WO | disclosed |
| WO-2003046132-A2 | ANTISENSE MODULATION OF MYD88 EXPRESSION | ISIS PHARMACEUTICALS, INC. (US) | 2003-06-05 | — | — | WO | disclosed |
| WO-2002020549-A1 | ANTISENSE MODULATION OF GLIOMA-ASSOCIATED ONCOGENE-1 EXPRESSION | ISIS PHARMACEUTICALS, INC. (US) | 2002-03-14 | — | — | WO | disclosed |