Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7901416 | 1.00 | DNPH1 (0.38) | DNPH1TK2 | |
| SCHEMBL313035 | 0.91 | TK2 (0.41) | TK2 | |
| SCHEMBL260669 | 0.91 | TK2 (0.41) | TK2 | |
| SCHEMBL8171834 | 0.91 | DNPH1 (0.41) | DNPH1TK2 | |
| SCHEMBL8171833 | 0.91 | DNPH1 (0.41) | DNPH1TK2 | |
| SCHEMBL6851560 | 0.87 | DNPH1 (0.50) | DNPH1 | |
| SCHEMBL1738250 | 0.86 | TK2 (0.42) | TK2 | |
| SCHEMBL7065021 | 0.83 | TK2 (0.42) | TK2 | |
| SCHEMBL7065019 | 0.83 | TK2 (0.42) | TK2 | |
| SCHEMBL10646803 | 0.82 | DNPH1 (0.40) | DNPH1TK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187586-B1 | NUCLEOTIDE SEQUENCE OF COMPOUND WHICH INHIBITS EXPRESSION OF HUMAN SERINE/THREONINE KINASE INVOLVED IN SIGNAL TRANSDUCTION; DIAGNOSIS, PROPHYLAXIS, AND THERAPY OF RELATED DISEASES | ISIS PHARMACEUTICALS, INC. | 2001-02-13 | — | — | US | disclosed |
| US-6140126-A | OLIGONUCLEOTIDES WHICH TARGET UNTRANSLATED REGIONS CODING A TRANSCRIPTION FACTOR; FOR TREATMENT OF CANCER AND INFLAMAMATION; ANTICARCINOGENIC AGENTS; ANTIINFLAMMATORY AGENTS | ISIS PHARMACEUTICALS INC. (US) | 2000-10-31 | — | — | US | disclosed |
| US-6140125-A | NUCLEOTIDE SEQUENCES WHICH TARGET START CODON AND UNTRANSLATED POSITIONING OF A CODED PROTEIN; FOR THE DIAGNOSIS OF TUMORS AND INFLAMMATION; ANTIINFLAMMATORY AGENTS; ANTITUMOR AGENTS | ISIS PHARMACEUTICALS INC. (US) | 2000-10-31 | — | — | US | disclosed |